Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia.
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Nitric oxide and peroxynitrite in health and diseaseSOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathwaysProteomic analysis of pulmonary edema fluid and plasma in patients with acute lung injury.Hypoxia inducible factor 1alpha signaling in fractionated radiation-induced lung injury: role of oxidative stress and tissue hypoxia.Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: rodent models of ischemic stroke and subarachnoid hemorrhageNeuroprotection against superoxide anion radical by metallocorroles in cellular and murine models of optic neuropathy.Catalytic antioxidants and neurodegenerationSuperoxide dismutase mimics: chemistry, pharmacology, and therapeutic potentialLong-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat.The neuroprotective properties of the superoxide dismutase mimetic tempol correlate with its ability to reduce pathological glutamate release in a rodent model of stroke.Neuroprotective efficacy and therapeutic time window of peroxynitrite decomposition catalysts in focal cerebral ischemia in ratsEffect of lipophilicity of Mn (III) ortho N-alkylpyridyl- and diortho N, N'-diethylimidazolylporphyrins in two in-vitro models of oxygen and glucose deprivation-induced neuronal death.Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimicsA redox signature score identifies diffuse large B-cell lymphoma patients with a poor prognosisMn porphyrin-based superoxide dismutase (SOD) mimic, MnIIITE-2-PyP5+, targets mouse heart mitochondriaA new SOD mimic, Mn(III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity.6-Hydroxydopamine induces mitochondrial ERK activation.Reactive oxygen species mediate cognitive deficits in experimental temporal lobe epilepsy.SOD-like activity of Mn(II) beta-octabromo-meso-tetrakis(N-methylpyridinium-3-yl)porphyrin equals that of the enzyme itselfPharmacokinetics of the potent redox-modulating manganese porphyrin, MnTE-2-PyP(5+), in plasma and major organs of B6C3F1 miceCatalase and glutathione peroxidase mimics.Comprehensive pharmacokinetic studies and oral bioavailability of two Mn porphyrin-based SOD mimics, MnTE-2-PyP5+ and MnTnHex-2-PyP5+.Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins.Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators.Therapeutic potential of peroxynitrite decomposition catalysts: a patent review.Regulation of mitophagy in ischemic brain injury.Oxidative Stress Induced by MnSOD-p53 Interaction: Pro- or Anti-Tumorigenic?Evaluation of the anti-oxidant properties of a SOD-mimic Mn-complex in activated macrophages.Metalloporphyrin antioxidants ameliorate normal tissue radiation damage in rat brain.Suppression of reactive oxygen species production enhances neuronal survival in vitro and in vivo in the anoxia-tolerant turtle Trachemys scripta.Electrostatic contribution in the catalysis of O2*- dismutation by superoxide dismutase mimics. MnIIITE-2-PyP5+ versus MnIIIBr8T-2-PyP+.Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion.New class of potent catalysts of O2.-dismutation. Mn(III) ortho-methoxyethylpyridyl- and di-ortho-methoxyethylimidazolylporphyrins.Radioprotective effect of a metalloporphyrin compound in rat eye model.New PEG-ylated Mn(III) porphyrins approaching catalytic activity of SOD enzyme.Low molecular weight catalytic metalloporphyrin antioxidant AEOL 10150 protects lungs from fractionated radiation.The therapeutic effect of extracellular superoxide dismutase (EC-SOD) mouse embryonic fibroblast (MEF) on collagen-induced arthritis (CIA) mice.Unconventional neuroprotection against Ca2+ -dependent insults by metalloporphyrin catalytic antioxidants.The Differences in the Cellular and Plasma Antioxidative Capacity Between Transient and Defined Focal Brain Ischemia: Does it Suggest Supporting Time-Dependent Neuroprotection Therapy?Decreased hepatic ischemia-reperfusion injury by manganese-porphyrin complexes.
P2860
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P2860
Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia.
@en
Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia.
@nl
type
label
Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia.
@en
Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia.
@nl
prefLabel
Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia.
@en
Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia.
@nl
P2093
P1476
Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia.
@en
P2093
Brian J Day
Carla L Calvi
David S Warner
Huaxin Sheng
Ines Batinić-Haberle
James D Crapo
Manisha Patel
Robert D Pearlstein
Russell Bowler
P304
P356
10.1016/S0891-5849(02)00979-6
P577
2002-10-01T00:00:00Z