Low plasma progranulin levels predict progranulin mutations in frontotemporal lobar degeneration.
about
Molecular Pathways Bridging Frontotemporal Lobar Degeneration and Psychiatric DisordersExpanding the Repertoire of Biomarkers for Alzheimer's Disease: Targeted and Non-targeted ApproachesPhenotypic Heterogeneity of Monogenic Frontotemporal DementiaBiomarkers in dementia: clinical utility and new directionsPotential roles of microglial cell progranulin in HIV-associated CNS pathologies and neurocognitive impairmentA neurodegenerative disease mutation that accelerates the clearance of apoptotic cellsProgranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation.Progranulin gene variability and plasma levels in bipolar disorder and schizophrenia.Diagnostic and prognostic significance of neurofilament light chain NF-L, but not progranulin and S100B, in the course of amyotrophic lateral sclerosis: Data from the German MND-net.Evidence of the innate antiviral and neuroprotective properties of progranulin.Rs5848 variant influences GRN mRNA levels in brain and peripheral mononuclear cells in patients with Alzheimer's disease.Progranulin protein levels are differently regulated in plasma and CSF.Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging.Clinical phenotypes and genetic biomarkers of FTLD.Genetics of dementia.Progranulin gene (GRN) promoter methylation is increased in patients with sporadic frontotemporal lobar degeneration.Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin.Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma.TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers.Association between GRN rs5848 polymorphism and Parkinson's disease in Taiwanese populationrs5848 polymorphism and serum progranulin levelAssociation of TMEM106B gene polymorphism with age at onset in granulin mutation carriers and plasma granulin protein levels.Brain progranulin expression in GRN-associated frontotemporal lobar degenerationTDP-43 as a possible biomarker for frontotemporal lobar degeneration: a systematic review of existing antibodiesLow plasma progranulin levels in children with autism.TMEM106B a novel risk factor for frontotemporal lobar degenerationProgranulin: a growth factor, a novel TNFR ligand and a drug targetCerebrospinal Fluid P-Tau181P: Biomarker for Improved Differential Dementia Diagnosis.Plasma levels of progranulin and interleukin-6 in frontotemporal lobar degeneration.Membrane orientation and subcellular localization of transmembrane protein 106B (TMEM106B), a major risk factor for frontotemporal lobar degeneration.Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia.Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin.Decreased progranulin levels in patients and rats with subarachnoid hemorrhage: a potential role in inhibiting inflammation by suppressing neutrophil recruitment.Progranulin: a proteolytically processed protein at the crossroads of inflammation and neurodegeneration.Progranulin regulates neuronal outgrowth independent of sortilinNo major progranulin genetic variability contribution to disease etiopathogenesis in an ALS Italian cohort.Insights into the role of progranulin in immunity, infection, and inflammation.Cerebrospinal fluid biomarkers for differentiation of frontotemporal lobar degeneration from Alzheimer's disease.Secreted progranulin is a homodimer and is not a component of high density lipoproteins (HDL)Advances in understanding the molecular basis of frontotemporal dementia.
P2860
Q26766487-956D18C1-D6CB-473E-8695-A2951EC15499Q26770708-F41BFEDB-530A-42A4-8370-33D612DBD23FQ26782984-606B93B7-864B-4373-846B-620681FCB95FQ27007086-68459540-4CAD-4B2D-AE33-6EE2FD721217Q27011876-26748455-21CA-4518-964F-57F83BA39157Q30498840-4BC30FFD-5214-4E58-858C-FD709FBCA784Q30754508-9A55E21F-14A3-4DF6-91BE-E569A6FE3627Q31055209-3B369238-31EE-4035-8ACB-400DA8B2C43DQ31141202-648B200A-FFD5-42AF-B929-AB2BCEC617B3Q33690042-0368B9E6-2C4E-4083-88EF-F737A6E94EBDQ33742148-A537ABB4-9005-4109-A2F8-CB79956D2C06Q33927199-638D47FC-6C55-4E11-AEE0-B5F4E120043FQ33947272-C6B294E0-86C7-4A03-A73F-024F526B7E7EQ34243054-A6FB57EC-8AB7-4949-8D3E-C835736D9440Q34248849-0AA2F053-D8BD-4674-86D2-08AA69C1D4E9Q34338059-814EB041-5EA1-436C-87AD-6F1ABDFEE1BBQ34346014-4C7328BC-8E46-4298-819F-DE8D06715B62Q34381669-CC614FEB-363C-4C35-8AAA-84F2D417A34CQ34555400-6EF4D248-CB4F-416D-97A3-80BF940A11C9Q34559477-7CADD444-DEC4-4BD7-B173-AAD083715C86Q34891810-DE8A7D99-4FBA-4484-9DB8-D16B66A5212FQ34959322-761FB23E-DE69-4F5D-8571-BBA0587BECC6Q35014879-A163D000-C096-4973-BE6B-EA41D85C6264Q35234677-5FADCE3F-FFAF-4CBB-B182-B457F40FF092Q35240854-F21D8A90-3449-4E00-A7EE-C8B7ED32246FQ35512313-DFF4E7B3-0B83-4B42-B291-FA4CF3CB869EQ35601050-E77C670F-FAAD-4AF9-924B-2B74EC8570BAQ35750755-CD4AC6A2-22EB-42FD-9568-F4C6CF9E683DQ35859333-2C16F9E8-CF04-450C-BDCF-10D79D9F0E6DQ36003800-75578595-0DFD-4A3D-981E-695A79EBCF83Q36061223-A9ED42C7-B66A-4C6C-8CBE-5CC1A79A7CDCQ36078240-22373904-1B2A-4395-9C4A-125C86096246Q36242938-D55308F1-BCF6-452F-AA95-7620DED64037Q36294670-97ABC84E-F6F8-429A-ABF0-305BFC36804DQ36430434-DBE81A05-719C-471F-82A8-4B7519F32B16Q36438687-5B8B3ECC-50E4-4658-B676-2EABC8AE73EEQ36534831-1E5E0A63-0455-456D-A481-D86755C8A9F7Q36626657-2229E0CF-4B9E-4AC1-8632-25E1162D85C8Q36708664-C916119B-1A07-450A-BE19-3F6E6CD978C1Q36775677-5CD851A7-AB84-470E-894A-B2AFA2F8EF9F
P2860
Low plasma progranulin levels predict progranulin mutations in frontotemporal lobar degeneration.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Low plasma progranulin levels ...... totemporal lobar degeneration.
@en
type
label
Low plasma progranulin levels ...... totemporal lobar degeneration.
@en
prefLabel
Low plasma progranulin levels ...... totemporal lobar degeneration.
@en
P50
P1433
P1476
Low plasma progranulin levels ...... ntotemporal lobar degeneration
@en
P2093
P304
P356
10.1212/01.WNL.0000325058.10218.FC
P407
P577
2008-09-03T00:00:00Z