Ligand-insensitive state of cardiac ATP-sensitive K+ channels. Basis for channel opening.
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ATP-sensitive potassium channels mediate survival during infection in mammals and insectsHow ATP inhibits the open K(ATP) channelATP interaction with the open state of the K(ATP) channel.Activation of ATP-sensitive K(+) channels by epoxyeicosatrienoic acids in rat cardiac ventricular myocytesCholesterol regulates glucose-stimulated insulin secretion through phosphatidylinositol 4,5-bisphosphate.Modulation of K(ATP) currents in rat ventricular myocytes by hypoxia and a redox reactionKATP channels gated by intracellular nucleotides and phospholipids.Mutations within the P-loop of Kir6.2 modulate the intraburst kinetics of the ATP-sensitive potassium channel.The kinetic and physical basis of K(ATP) channel gating: toward a unified molecular understanding.Concerted gating mechanism underlying KATP channel inhibition by ATP.Cellular remodeling in heart failure disrupts K(ATP) channel-dependent stress toleranceGating mechanism of KATP channels: function fits form.Pharmacological plasticity of cardiac ATP-sensitive potassium channels toward diazoxide revealed by ADPATP-sensitive K+ channel channel/enzyme multimer: metabolic gating in the heart.Adenylate kinase phosphotransfer communicates cellular energetic signals to ATP-sensitive potassium channelsKATP Channels in the Cardiovascular System.Phosphoinositides decrease ATP sensitivity of the cardiac ATP-sensitive K(+) channel. A molecular probe for the mechanism of ATP-sensitive inhibitionRegulation of cloned ATP-sensitive K channels by phosphorylation, MgADP, and phosphatidylinositol bisphosphate (PIP(2)): a study of channel rundown and reactivationOpen state destabilization by ATP occupancy is mechanism speeding burst exit underlying KATP channel inhibition by ATP.Role for SUR2A ED domain in allosteric coupling within the K(ATP) channel complex.Ligand-dependent linkage of the ATP site to inhibition gate closure in the KATP channelATP-sensitive potassium channels: metabolic sensing and cardioprotection.Alternative splicing of sur2 Exon 17 regulates nucleotide sensitivity of the ATP-sensitive potassium channel.ATP-sensitive K+ channels: regulation of bursting by the sulphonylurea receptor, PIP2 and regions of Kir6.2.Activation of the K(ATP) channel by Mg-nucleotide interaction with SUR1.Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A KATP channels: a mechanistic studyControl of Kir channel gating by cytoplasmic domain interface interactionsEffect of metabolic inhibition on glimepiride block of native and cloned cardiac sarcolemmal K(ATP) channels.Tandem function of nucleotide binding domains confers competence to sulfonylurea receptor in gating ATP-sensitive K+ channels.Phosphatidic acid stimulates cardiac KATP channels like phosphatidylinositols, but with novel gating kinetics.Analysis of the differential modulation of sulphonylurea block of beta-cell and cardiac ATP-sensitive K+ (K(ATP)) channels by Mg-nucleotides.A mutation in the ATP-binding site of the Kir6.2 subunit of the KATP channel alters coupling with the SUR2A subunit.
P2860
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P2860
Ligand-insensitive state of cardiac ATP-sensitive K+ channels. Basis for channel opening.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Ligand-insensitive state of cardiac ATP-sensitive K+ channels. Basis for channel opening.
@en
type
label
Ligand-insensitive state of cardiac ATP-sensitive K+ channels. Basis for channel opening.
@en
prefLabel
Ligand-insensitive state of cardiac ATP-sensitive K+ channels. Basis for channel opening.
@en
P2093
P2860
P356
P1476
Ligand-insensitive state of cardiac ATP-sensitive K+ channels. Basis for channel opening.
@en
P2093
P2860
P304
P356
10.1085/JGP.111.2.381
P577
1998-02-01T00:00:00Z