The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores
about
Molecular cloning and sequence analysis of hamster CENP-A cDNA.INCENP centromere and spindle targeting: identification of essential conserved motifs and involvement of heterochromatin protein HP1Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APCUnstable microtubule capture at kinetochores depleted of the centromere-associated protein CENP-F.Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction.Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritanceZW10 links mitotic checkpoint signaling to the structural kinetochore.CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelityConservation of the centromere/kinetochore protein ZW10Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint.The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinaseProbing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpointCentromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome lossIdentification of a MAD2-binding protein, CMT2, and its role in mitosis.A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targetingHec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint controlSil phosphorylation in a Pin1 binding domain affects the duration of the spindle checkpointBub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochoresUncoupling the central spindle-associated function of the chromosomal passenger complex from its role at centromeresLesions in many different spindle components activate the spindle checkpoint in the budding yeast Saccharomyces cerevisiaeMicrotubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochoresConformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpointMammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpointsCytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivationThe centromere geometry essential for keeping mitosis error free is controlled by spindle forcesTaxol suppresses dynamics of individual microtubules in living human tumor cellsCheckpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2Aberrantly segregating centromeres activate the spindle assembly checkpoint in budding yeastThe small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpointMicrotubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signalingSpindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activityKinetochore fiber maturation in PtK1 cells and its implications for the mechanisms of chromosome congression and anaphase onsetAssembly of CENP-A into centromeric chromatin requires a cooperative array of nucleosomal DNA contact sitesSpindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochoresMammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events.HURP controls spindle dynamics to promote proper interkinetochore tension and efficient kinetochore capture.Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphaseThe Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint SignalingCentrosomes, chromosome instability (CIN) and aneuploidyDNA damage associated with mitosis and cytokinesis failure
P2860
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P2860
The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores
description
1995 nî lūn-bûn
@nan
1995 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
The checkpoint delaying anapha ...... ced by unattached kinetochores
@ast
The checkpoint delaying anapha ...... ced by unattached kinetochores
@en
The checkpoint delaying anapha ...... ced by unattached kinetochores
@nl
type
label
The checkpoint delaying anapha ...... ced by unattached kinetochores
@ast
The checkpoint delaying anapha ...... ced by unattached kinetochores
@en
The checkpoint delaying anapha ...... ced by unattached kinetochores
@nl
prefLabel
The checkpoint delaying anapha ...... ced by unattached kinetochores
@ast
The checkpoint delaying anapha ...... ced by unattached kinetochores
@en
The checkpoint delaying anapha ...... ced by unattached kinetochores
@nl
P2093
P2860
P356
P1476
The checkpoint delaying anapha ...... ced by unattached kinetochores
@en
P2093
P2860
P356
10.1083/JCB.130.4.941
P407
P577
1995-08-01T00:00:00Z