A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies - Test2 - elhamkhani - TriplyDB

A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies

A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies

http://www.wikidata.org/entity/Q28299280

about

Dynamic Viral Glycoprotein Machines: Approaches for Probing Transient States That Drive Membrane Fusion Structural and Computational Biology in the Design of Immunogenic Vaccine Antigens The HIV glycan shield as a target for broadly neutralizing antibodies Recent strategies targeting HIV glycans in vaccine design Structural insights on the role of antibodies in HIV-1 vaccine and therapy Antibody responses to envelope glycoproteins in HIV-1 infection Structure and Dynamics of the Native HIV-1 Env Trimer A Chimeric HIV-1 gp120 Fused with Vaccinia Virus 14K (A27) Protein as an HIV Immunogen Computational Refinement and Validation Protocol for Proteins with Large Variable Regions Applied to Model HIV Env Spike in CD4 and 17b Bound State.Antigenic properties of the human immunodeficiency virus envelope glycoprotein gp120 on virions bound to target cells Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers.Progress in HIV-1 vaccine development.Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site New concepts in HIV-1 vaccine development Protein Crystallography in Vaccine Research and Development Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers Cell- and Protein-Directed Glycosylation of Native Cleaved HIV-1 Envelope Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes An efficiently cleaved HIV-1 clade C Env selectively binds to neutralizing antibodies Thermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing Antibodies HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers Structure of 2G12 Fab2 in complex with soluble and fully glycosylated HIV-1 Env by negative-stain single-particle electron microscopy Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies.Pre-fusion structure of a human coronavirus spike protein.Current views on the potential for development of a HIV vaccine.Stabilized HIV-1 envelope glycoprotein trimers for vaccine use.Antigenic and 3D structural characterization of soluble X4 and hybrid X4-R5 HIV-1 Env trimers Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.Human antibody pieces together the puzzle of the trimeric Lassa virus surface antigen.Lessons learned from human HIV vaccine trials.

P2860

Q26772129-711C7C41-8B86-4A83-87FE-D1F5E001AE7E Q26777382-2CFB00D8-8909-4B59-B037-FEA00129CA49 Q26786540-C9870DA6-6B49-4483-A6B7-02F07A7B9C4F Q26823603-F1326FEC-5A4A-4824-996A-3062A738E59A Q26829461-E002877D-E25B-4E47-9749-DC0E05025423 Q26991572-49F559A8-304B-4516-A65B-646F0508D8A0 Q27027570-B0AB2B8C-C78F-41BD-B1AF-7F424F0BFEA4 Q27302081-FE594CAA-13AD-4047-90D2-EE7ED54C895F Q27303608-218C0C45-9380-4A73-A2E2-C934815C921F Q27320687-AFAEB23A-8E20-4D2D-B59C-777E149367D2 Q27644383-E847EC60-BAE9-4205-922A-10FE7EE710A1 Q27644415-BEDE14C3-0A95-42B6-B7F2-8E050ADC91D8 Q27644634-DD71DB8F-0100-4267-9DF7-26F9E687C6FD Q27680496-144B17B4-9332-49A7-8807-933E0BC61E66 Q27680497-E7E9F4DC-70C7-410E-879A-29BFB4A86AA7 Q27683540-CB3F8306-A616-4AEB-A333-AAB94D852EDD Q27683553-7CDD3839-56F8-4F68-967A-9D91995CACA5 Q27693849-1437A669-3802-43F0-B306-9B7333305187 Q27704710-E030620E-B977-424D-9007-208508FF837C Q27723297-93C5D4BD-DE75-4F0F-A326-EE7AF2FC8726 Q27728037-1F62881A-768E-43E6-8B6C-59A7D7D6F098 Q28067027-2B64F336-5093-4D16-AE0E-B2C238BDB1E4 Q28087528-7004E5DE-C61D-4CEB-8009-46D3BF4CDC65 Q28256508-651BE70F-A95E-45DB-81BC-CB157D8DF1F1 Q28263063-8BCC797B-9EA7-411D-A59E-C28756E77067 Q28263655-B1FD88FF-4C57-4072-8590-59E0F25040EF Q28271300-FECAD0DE-AB83-49DC-AC6F-581745224A87 Q28545185-5A7E121A-D2E5-4C5E-A929-DA9EFD9062CA Q28553360-5F472560-FFE6-4522-BCD4-124337F693D6 Q28647225-4C356909-F9FC-4FA6-B89F-ED88A426FACC Q28654490-AE448CC0-0173-4834-9011-8C9EC5CAFBD5 Q29306052-F829D616-D767-47F0-8E04-FDF36D957F5D Q30352300-48AF2A0C-5A50-4E27-B034-559C25CDEB2E Q30385177-767ECB5D-1E7B-4E4B-9685-97E4F33D5A0E Q30397595-CD3C1349-624C-43D1-BBDA-3B442B2EF229 Q30490942-0CC82131-2543-452D-BECF-37BF7C8DDDE4 Q30580101-D4FC35A7-9713-4C67-A6A1-D3ECB5486456 Q30657338-EFFE0683-B75A-4E83-8928-B595CB0D7492 Q33365688-8518DD8C-4414-4119-88D3-33E1155A3853 Q33557844-1E19DA17-1F6A-4E12-9E67-04E7CBB6A178

P2860

A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies

http://www.wikidata.org/entity/Q28299280

description

2013 nî lūn-bûn

@nan

2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

A next-generation cleaved, sol ...... ot non-neutralizing antibodies

@ast

A next-generation cleaved, sol ...... ot non-neutralizing antibodies

@en

A next-generation cleaved, sol ...... ot non-neutralizing antibodies

@nl

type

label

A next-generation cleaved, sol ...... ot non-neutralizing antibodies

@ast

A next-generation cleaved, sol ...... ot non-neutralizing antibodies

@en

A next-generation cleaved, sol ...... ot non-neutralizing antibodies

@nl

prefLabel

A next-generation cleaved, sol ...... ot non-neutralizing antibodies

@ast

A next-generation cleaved, sol ...... ot non-neutralizing antibodies

@en

A next-generation cleaved, sol ...... ot non-neutralizing antibodies

@nl

P1433

Q28299280-2972BB06-A4C1-4E06-A391-CB0C78987A3D

P1476

Q28299280-69FF5705-1E4F-43CA-AF9D-0FE408F99B78

P2093

Q28299280-0B167387-4A50-4D3D-8FB6-D38FB59403AA

Q28299280-15234FFA-6CA6-4D0A-9F7C-C4965DC561F1

Q28299280-1BE0D93A-F76F-4D63-B6E5-0ECB4E586A78

Q28299280-1DE24D66-9A82-419A-B2F5-12B9C3AF3A68

Q28299280-3DE2F6E1-405F-4D5F-BBC9-5354FD78DE47

Q28299280-50A1F1CF-D8A2-481B-95B2-510F95562693

Q28299280-542D25BC-6CD3-4592-AF6B-663A5C903D52

Q28299280-6511D342-FEA2-4DD3-9474-C17136A8C182

Q28299280-808F015E-1D67-493A-B468-9E0F0BA98A85

Q28299280-92FE33BD-6487-45A7-A07F-FB6BEFF19002

P2860

Q28299280-05987151-50E4-4A40-A0A9-19E578A150C2

Q28299280-0C9C3FCA-804B-47A5-A410-8CE6435AE5E8

Q28299280-0CA80029-95F1-4F75-8AB2-8EE4B93EBF13

Q28299280-0D5F12D9-1C14-491C-B1F8-E9953DB985D1

Q28299280-0E020D31-1E4B-4B24-B733-F280DBFB3FA2

Q28299280-0F1A055F-2653-458A-AD1C-D10FCE332451

Q28299280-111558A9-9A90-410A-BDC1-90FB6E0E9862

Q28299280-112B1B86-FE63-4C2B-A8DC-B6E366217C14

Q28299280-17486AA8-5D94-42DC-8C05-015177F9F7CB

Q28299280-18069CAB-CD1B-4D7F-9DDA-823CED795978

P304

Q28299280-4E82EDA7-8174-43CC-A720-A4C06B152002

P31

Q28299280-543CF916-5AE7-4F5F-B748-8BC365F16AF8

P3181

Q28299280-CE029511-AC47-4241-A313-4140750A2FBB

P356

Q28299280-79FC32D2-05C5-4610-B815-6537F9F25696

P407

Q28299280-0BF02052-5617-479F-A35D-1980E53F8499

P433

Q28299280-C164B1C6-8445-464F-BDDB-64AD5B4A45EE

P478

Q28299280-83B9B7C9-DEC7-4FD1-B742-631FD65C8FA4

P50

Q28299280-0A3134E9-C992-485C-A89B-FF7E9D99D583

Q28299280-49572505-CB65-476B-A737-236262FB1655

Q28299280-6515626C-7EB3-4D2A-AB7D-B788EF581F03

P577

Q28299280-7F65011F-EE9C-4C1A-8FFD-7B9637F47B54

P5875

Q28299280-0DFE5FA2-CA47-41B5-B35F-FD8C47886256

P698

Q28299280-B286B47F-61FB-4AB3-81A1-9AF9E3D542D5

P921

Q28299280-CD7BB698-47C6-488A-BF18-950EEFD03613

P932

Q28299280-B013AE5B-F2D7-4860-BDD8-1BDF2B5FCB88

P3181

P356

JOURNAL.PPAT.1003618

P1433

P1476

A next-generation cleaved, sol ...... ot non-neutralizing antibodies

@en

P2093

Alba Torrents de la Peña

http://www.w3.org/2001/XMLSchema#string

Albert Cupo

http://www.w3.org/2001/XMLSchema#string

Andrew B Ward

http://www.w3.org/2001/XMLSchema#string

Anila Yasmeen

http://www.w3.org/2001/XMLSchema#string

C Richter King

http://www.w3.org/2001/XMLSchema#string

Claudia Blattner

http://www.w3.org/2001/XMLSchema#string

Helen J Kim

http://www.w3.org/2001/XMLSchema#string

Jacob Korzun

http://www.w3.org/2001/XMLSchema#string

John P Moore

http://www.w3.org/2001/XMLSchema#string

Kevin de Los Reyes

http://www.w3.org/2001/XMLSchema#string

P2860

Structural mechanism of trimeric HIV-1 envelope glycoprotein activation

Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120

Molecular architecture of native HIV-1 gp120 trimers

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans

Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120

EMAN: semiautomated software for high-resolution single-particle reconstructions

EMAN2: an extensible image processing suite for electron microscopy

P304

e1003618

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

190582

http://www.w3.org/2001/XMLSchema#string

P356

10.1371/JOURNAL.PPAT.1003618

http://www.w3.org/2001/XMLSchema#string

P407

P433

9

http://www.w3.org/2001/XMLSchema#string

P478

9

http://www.w3.org/2001/XMLSchema#string

P50

Jean-Philippe Julien

Marit J van Gils

Ian Andrew Wilson

P577

2013-09-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

257075097

http://www.w3.org/2001/XMLSchema#string

P698

24068931

http://www.w3.org/2001/XMLSchema#string

P921

P932

3777863

http://www.w3.org/2001/XMLSchema#string