Insights into protein kinase regulation and inhibition by large scale structural comparison
about
Affinity-Based Probes Based on Type II Kinase InhibitorsA Conserved Glu–Arg Salt Bridge Connects Coevolved Motifs That Define the Eukaryotic Protein Kinase FoldDe Novo Design of Protein Kinase Inhibitors by in Silico Identification of Hinge Region-Binding FragmentsSelectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase InhibitorsDifferential inhibitor sensitivity between human kinases VRK1 and VRK2.Oncogenic potential is related to activating effect of cancer single and double somatic mutations in receptor tyrosine kinasesCatalytic control in the EGF receptor and its connection to general kinase regulatory mechanisms.Protein kinase-inhibitor database: structural variability of and inhibitor interactions with the protein kinase P-loop.Structural and mechanistic insights into the bifunctional enzyme isocitrate dehydrogenase kinase/phosphatase AceK.Multiple steps to activate FAK's kinase domain: adaptation to confined environments?Variability of disease spectrum in children with liver phosphorylase kinase deficiency caused by mutations in the PHKG2 gene.Perspective of cyclin-dependent kinase 9 (CDK9) as a drug target.Structural and functional diversity in the activity and regulation of DAPK-related protein kinases.Designing selective inhibitors for calcium-dependent protein kinases in apicomplexans.Understanding how cAMP-dependent protein kinase can catalyze phosphoryl transfer in the presence of Ca2+ and Sr2+: a QM/MM study.Novel approaches for targeting kinases: allosteric inhibition, allosteric activation and pseudokinases.Expressing the human proteome for affinity proteomics: optimising expression of soluble protein domains and in vivo biotinylation.Interaction network of the ribosome assembly machinery from a eukaryotic thermophile.Mechanism of dual specificity kinase activity of DYRK1A.
P2860
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P2860
Insights into protein kinase regulation and inhibition by large scale structural comparison
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Insights into protein kinase r ...... ge scale structural comparison
@ast
Insights into protein kinase r ...... ge scale structural comparison
@en
type
label
Insights into protein kinase r ...... ge scale structural comparison
@ast
Insights into protein kinase r ...... ge scale structural comparison
@en
prefLabel
Insights into protein kinase r ...... ge scale structural comparison
@ast
Insights into protein kinase r ...... ge scale structural comparison
@en
P2860
P1476
Insights into protein kinase r ...... ge scale structural comparison
@en
P2093
Jeyanthy Eswaran
P2860
P304
P356
10.1016/J.BBAPAP.2009.10.013
P407
P50
P577
2009-10-22T00:00:00Z
2010-03-01T00:00:00Z