Telomere protection by TPP1/POT1 requires tethering to TIN2
about
P1343
TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwindingInvolvement of telomerase reverse transcriptase in heterochromatin maintenance53BP1: pro choice in DNA repairTelomeres-structure, function, and regulationMultiple facets of TPP1 in telomere maintenanceImplications of telomeres and telomerase in endometrial pathologyA three-state model for the regulation of telomerase by TERRA and hnRNPA1Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formationMolecular Architecture of Full-length TRF1 Favors Its Interaction with DNAThe Drosophila telomere-capping protein Verrocchio binds single-stranded DNA and protects telomeres from DNA damage response.Human RECQL1 participates in telomere maintenanceAkt regulates TPP1 homodimerization and telomere protection.PRL-3 promotes telomere deprotection and chromosomal instability.POT1-TPP1 regulates telomeric overhang structural dynamics.Crosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis.Binding of TPP1 protein to TIN2 protein is required for POT1a,b protein-mediated telomere protection.RPA and POT1: friends or foes at telomeres?Hoyeraal-Hreidarsson syndrome caused by a germline mutation in the TEL patch of the telomere protein TPP1.Removal of shelterin reveals the telomere end-protection problem.Unraveling the pathogenesis of Hoyeraal-Hreidarsson syndrome, a complex telomere biology disorderTRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling.Cell cycle regulated phosphorylation of the telomere-associated protein TIN2Tpz1 controls a telomerase-nonextendible telomeric state and coordinates switching to an extendible state via Ccq1.G-quadruplex formation in telomeres enhances POT1/TPP1 protection against RPA binding.Defective repair of uracil causes telomere defects in mouse hematopoietic cells.Telomeric overhang length determines structural dynamics and accessibility to telomerase and ALT-associated proteinsHuman Rap1 modulates TRF2 attraction to telomeric DNA.Tpz1-Ccq1 and Tpz1-Poz1 interactions within fission yeast shelterin modulate Ccq1 Thr93 phosphorylation and telomerase recruitment.The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres.Dissecting Fission Yeast Shelterin Interactions via MICro-MS Links Disruption of Shelterin Bridge to TumorigenesisShelterin Protects Chromosome Ends by Compacting Telomeric ChromatinSMARCAL1 maintains telomere integrity during DNA replication.A three-state model of telomere control over human proliferative boundaries.Complex interactions between the DNA-damage response and mammalian telomeres.Telomere structure and telomerase in health and disease (review).Replication of telomeres and the regulation of telomerase.DNA repair at telomeres: keeping the ends intact.The shelterin complex and hematopoiesis.A two-step mechanism for TRF2-mediated chromosome-end protection.TRF2-Mediated Control of Telomere DNA Topology as a Mechanism for Chromosome-End Protection
P2860
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P2860
Telomere protection by TPP1/POT1 requires tethering to TIN2
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Telomere protection by TPP1/POT1 requires tethering to TIN2
@ast
Telomere protection by TPP1/POT1 requires tethering to TIN2
@en
type
label
Telomere protection by TPP1/POT1 requires tethering to TIN2
@ast
Telomere protection by TPP1/POT1 requires tethering to TIN2
@en
prefLabel
Telomere protection by TPP1/POT1 requires tethering to TIN2
@ast
Telomere protection by TPP1/POT1 requires tethering to TIN2
@en
P2093
P2860
P1433
P1476
Telomere protection by TPP1/POT1 requires tethering to TIN2
@en
P2093
David Frescas
Jill R Donigian
Kaori K Takai
Tatsuya Kibe
P2860
P304
P356
10.1016/J.MOLCEL.2011.08.043
P4510
P577
2011-11-01T00:00:00Z