about
Progressive degeneration of human neural stem cells caused by pathogenic LRRK2Synaptic vesicle trafficking and Parkinson's diseaseUnbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson diseaseOxidative stress-induced signaling pathways implicated in the pathogenesis of Parkinson's diseasePharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease.Lipopolyplex for Therapeutic Gene Delivery and Its Application for the Treatment of Parkinson's DiseaseEmerging preclinical pharmacological targets for Parkinson's diseaseThere's Something Wrong with my MAM; the ER-Mitochondria Axis and Neurodegenerative DiseasesUbiquitin phosphorylation in Parkinson's disease: Implications for pathogenesis and treatmentCellular models to investigate biochemical pathways in Parkinson's diseaseEmerging modes of PINK1 signaling: another task for MARK2Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutationsUse of cysteine-reactive cross-linkers to probe conformational flexibility of human DJ-1 demonstrates that Glu18 mutations are dimersRevisiting the Roco G-protein cycleProtein Kinases and Parkinson's DiseaseThe parkin-like human homolog of Drosophila ariadne-1 (HHARI) can induce aggresome formation in mammalian cells and is immunologically detectable in Lewy bodiesMicrotubule affinity-regulating kinase 2 (MARK2) turns on phosphatase and tensin homolog (PTEN)-induced kinase 1 (PINK1) at Thr-313, a mutation site in Parkinson disease: effects on mitochondrial transportSomatic alpha-synuclein mutations in Parkinson's disease: hypothesis and preliminary data.Solving the puzzle of Parkinson's disease using induced pluripotent stem cells.Brain mitochondria from DJ-1 knockout mice show increased respiration-dependent hydrogen peroxide consumption.Arsenite stress down-regulates phosphorylation and 14-3-3 binding of leucine-rich repeat kinase 2 (LRRK2), promoting self-association and cellular redistributionRole of LRRK2 kinase dysfunction in Parkinson diseaseMicroRNA-7 protects against 1-methyl-4-phenylpyridinium-induced cell death by targeting RelA.Neurogenetics: advancing the "next-generation" of brain research.Dopaminergic neuronal loss and dopamine-dependent locomotor defects in Fbxo7-deficient zebrafish.Ursocholanic acid rescues mitochondrial function in common forms of familial Parkinson's disease.Molecular insights into Parkinson's disease.Ubiquitination increases parkin activity to promote autophagic α-synuclein clearance.Post-translational modifications of tubulin: pathways to functional diversity of microtubules.Age and α-synuclein expression interact to reveal a dependence of dopaminergic axons on endogenous Akt/PKB signaling.Past, present and future of A(2A) adenosine receptor antagonists in the therapy of Parkinson's disease.Animal models of Parkinson's disease: a source of novel treatments and clues to the cause of the disease.Mitochondrial quality control and dynamics in Parkinson's diseaseThe role of quercetin on the survival of neuron-like PC12 cells and the expression of α-synucleinα-Synuclein overexpressing transgenic mice show internal organ pathology and autonomic deficitsPhysiological phenotype and vulnerability in Parkinson's diseaseEnhanced J-protein interaction and compromised protein stability of mtHsp70 variants lead to mitochondrial dysfunction in Parkinson's diseaseRobust glyoxalase activity of Hsp31, a ThiJ/DJ-1/PfpI family member protein, is critical for oxidative stress resistance in Saccharomyces cerevisiae.Differential submitochondrial localization of PINK1 as a molecular switch for mediating distinct mitochondrial signaling pathways.Parkin ubiquitinates Tar-DNA binding protein-43 (TDP-43) and promotes its cytosolic accumulation via interaction with histone deacetylase 6 (HDAC6).
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Parkinson's disease: insights from pathways.
@ast
Parkinson's disease: insights from pathways.
@en
type
label
Parkinson's disease: insights from pathways.
@ast
Parkinson's disease: insights from pathways.
@en
prefLabel
Parkinson's disease: insights from pathways.
@ast
Parkinson's disease: insights from pathways.
@en
P2860
P356
P1476
Parkinson's disease: insights from pathways.
@en
P2093
Oliver Bandmann
P2860
P356
10.1093/HMG/DDQ167
P577
2010-04-26T00:00:00Z