An unusual active site identified in a family of zinc metalloendopeptidases
about
The genome of the leaf-cutting ant Acromyrmex echinatior suggests key adaptations to advanced social life and fungus farming.Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanismEvolutionary families of peptidasesMolecular basis for the thiol sensitivity of insulin-degrading enzymeMolecular Bases for the Recognition of Short Peptide Substrates and Cysteine-Directed Modifications of Human Insulin-Degrading Enzyme †Crystal and Solution Structures of a Prokaryotic M16B Peptidase: an Open and Shut CaseDesigned Inhibitors of Insulin-Degrading Enzyme Regulate the Catabolism and Activity of InsulinStructural analysis of cytochrome bc1 complexes: implications to the mechanism of functionYeast Ste23p shares functional similarities with mammalian insulin-degrading enzymes.The metalloprotease encoded by ATP23 has a dual function in processing and assembly of subunit 6 of mitochondrial ATPase.Insulin-degrading enzyme rapidly removes the beta-amyloid precursor protein intracellular domain (AICD)The beta subunit of the mitochondrial processing peptidase from rat liver: cloning and sequencing of a cDNA and comparison with a proposed family of metallopeptidasesA role for falcilysin in transit peptide degradation in the Plasmodium falciparum apicoplastIdentification and characterization of falcilysin, a metallopeptidase involved in hemoglobin catabolism within the malaria parasite Plasmodium falciparumProcessing of an apicoplast leader sequence in Plasmodium falciparum and the identification of a putative leader cleavage enzymeThe HIT protein family: a new family of proteins present in prokaryotes, yeast and mammals.Differential degradation of amyloid beta genetic variants associated with hereditary dementia or stroke by insulin-degrading enzyme.Mutational analysis of the potential catalytic residues of the VV G1L metalloproteinase.The pyrroloquinoline quinone biosynthesis pathway revisited: a structural approach.A chloroplast processing enzyme involved in precursor maturation shares a zinc-binding motif with a recently recognized family of metalloendopeptidases.Characterization of the bacterial metalloendopeptidase pitrilysin by use of a continuous fluorescence assay.Vaccinia virus G1 protein, a predicted metalloprotease, is essential for morphogenesis of infectious virions but not for cleavage of major core proteins.The closed structure of presequence protease PreP forms a unique 10,000 Angstroms3 chamber for proteolysis.Tn5-directed cloning of pqq genes from Pseudomonas fluorescens CHA0: mutational inactivation of the genes results in overproduction of the antibiotic pyoluteorin.Identification of human presequence protease (hPreP) agonists for the treatment of Alzheimer's disease.Synaptobrevin/vesicle-associated membrane protein (VAMP) of Aplysia californica: structure and proteolysis by tetanus toxin and botulinal neurotoxins type D and F.Families of metalloendopeptidases and their relationships.An in silico insight into novel therapeutic interaction of LTNF peptide-LT10 and design of structure based peptidomimetics for putative anti-diabetic activity.Insulin clearance in obesity.Vibrio vulnificus Secretes an Insulin-degrading Enzyme That Promotes Bacterial Proliferation in Vivo.Molecular dissection of novel trafficking and processing of the Toxoplasma gondii rhoptry metalloprotease toxolysin-1.Stromal processing peptidase binds transit peptides and initiates their ATP-dependent turnover in chloroplasts.A transcriptionally controlled trans-processing assay: putative identification of a vaccinia virus-encoded proteinase which cleaves precursor protein P25K.Two novel mitochondrial and chloroplastic targeting-peptide-degrading peptidasomes in A. thaliana, AtPreP1 and AtPreP2.Evolution of peptidase diversity.Expression of virus-encoded proteinases: functional and structural similarities with cellular enzymesAssembly of F0 in Saccharomyces cerevisiae.Proteolytic degradation of amyloid β-protein.Architecture and function of metallopeptidase catalytic domains.Insulin-degrading enzyme is exported via an unconventional protein secretion pathway.
P2860
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P2860
An unusual active site identified in a family of zinc metalloendopeptidases
description
1992 nî lūn-bûn
@nan
1992 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
An unusual active site identified in a family of zinc metalloendopeptidases
@ast
An unusual active site identified in a family of zinc metalloendopeptidases
@en
An unusual active site identified in a family of zinc metalloendopeptidases
@nl
type
label
An unusual active site identified in a family of zinc metalloendopeptidases
@ast
An unusual active site identified in a family of zinc metalloendopeptidases
@en
An unusual active site identified in a family of zinc metalloendopeptidases
@nl
prefLabel
An unusual active site identified in a family of zinc metalloendopeptidases
@ast
An unusual active site identified in a family of zinc metalloendopeptidases
@en
An unusual active site identified in a family of zinc metalloendopeptidases
@nl
P2860
P356
P1476
An unusual active site identified in a family of zinc metalloendopeptidases
@en
P2093
P2860
P304
P356
10.1073/PNAS.89.9.3835
P407
P577
1992-05-01T00:00:00Z