Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation - Wikidata - wikimedia - TriplyDB

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation

http://www.wikidata.org/entity/Q34300338

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Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains DTL/CDT2 is essential for both CDT1 regulation and the early G2/M checkpoint Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases.PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints Involvement of human MOF in ATM function A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16 Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints.Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2 Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair Involvement of nucleotide excision and mismatch repair mechanisms in double strand break repair Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance Dynamic Duo-The Salmonella Cytolethal Distending Toxin Combines ADP-Ribosyltransferase and Nuclease Activities in a Novel Form of the Cytolethal Distending Toxin Chemically enhanced radiotherapy: visions for the future DAB2IP in cancer Taselisib (GDC-0032), a Potent β-Sparing Small Molecule Inhibitor of PI3K, Radiosensitizes Head and Neck Squamous Carcinomas Containing Activating PIK3CA Alterations.DNA-PKcs-PIDDosome: a nuclear caspase-2-activating complex with role in G2/M checkpoint maintenance Transcriptional repression of Cdc25B by IER5 inhibits the proliferation of leukemic progenitor cells through NF-YB and p300 in acute myeloid leukemia The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins The effects of G2-phase enrichment and checkpoint abrogation on low-dose hyper-radiosensitivity Mutation of the mouse Rad17 gene leads to embryonic lethality and reveals a role in DNA damage-dependent recombination Epstein-Barr virus-encoded latent membrane protein 1 impairs G2 checkpoint in human nasopharyngeal epithelial cells through defective Chk1 activation DNA replication defects, spontaneous DNA damage, and ATM-dependent checkpoint activation in replication protein A-deficient cells.Topoisomerase II and histone deacetylase inhibitors delay the G2/M transition by triggering the p38 MAPK checkpoint pathway ATR-dependent checkpoint modulates XPA nuclear import in response to UV irradiation Chk1 kinase negatively regulates mitotic function of Cdc25A phosphatase through 14-3-3 binding Transient inhibition of ATM kinase is sufficient to enhance cellular sensitivity to ionizing radiation In vitro and in vivo radiosensitization with AZD6244 (ARRY-142886), an inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 kinase Microhomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex.Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX.MEPE/OF45 as a new target for sensitizing human tumour cells to DNA damage inducers Caffeine and human DNA metabolism: the magic and the mystery.Effects of ionizing radiation on biological molecules--mechanisms of damage and emerging methods of detection Vertebrate cells genetically deficient for Cdc14A or Cdc14B retain DNA damage checkpoint proficiency but are impaired in DNA repair.

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Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation

http://www.wikidata.org/entity/Q34300338

description

2002 nî lūn-bûn

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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

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2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

Two molecularly distinct G

@nl

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation

@ast

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation

@en

type

label

Two molecularly distinct G

@nl

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation

@ast

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation

@en

prefLabel

Two molecularly distinct G

@nl

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation

@ast

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation

@en

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P356

MCB.22.4.1049-1059.2002

P1433

Molecular and Cellular Biology

P1476

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation

@en

P2093

Bo Xu

http://www.w3.org/2001/XMLSchema#string

Dae-Sik Lim

http://www.w3.org/2001/XMLSchema#string

Michael B Kastan

http://www.w3.org/2001/XMLSchema#string

Seong-Tae Kim

http://www.w3.org/2001/XMLSchema#string

P2860

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

The DNA damage response: putting checkpoints in perspective

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses

The many substrates and functions of ATM

ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

P304

1049-1059

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scholarly article

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10.1128/MCB.22.4.1049-1059.2002

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134638

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