Analysis of the roles of 14-3-3 in the platelet glycoprotein Ib-IX-mediated activation of integrin alpha(IIb)beta(3) using a reconstituted mammalian cell expression model
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Sequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin alphaIIb beta3Association of Fyn and Lyn with the proline-rich domain of glycoprotein VI regulates intracellular signalingSelective association of protein kinase C with 14-3-3 zeta in neuronally differentiated PC12 Cells. Stimulatory and inhibitory effect of 14-3-3 zeta in vivoLateral clustering of platelet GP Ib-IX complexes leads to up-regulation of the adhesive function of integrin alpha IIbbeta 3Platelet biogenesis and functions require correct protein O-glycosylationThe role of platelets in acute lung injury (ALI)Heat-shock protein gp96/grp94 is an essential chaperone for the platelet glycoprotein Ib-IX-V complex.G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin "outside-in" signalingA thrombin receptor function for platelet glycoprotein Ib-IX unmasked by cleavage of glycoprotein V.Regulation of glycoprotein Ib-IX-von Willebrand factor interaction by cAMP-dependent protein kinase-mediated phosphorylation at Ser 166 of glycoprotein Ib(beta).Dynamic aspects of platelet adhesion under flow.Transmembrane domains are critical to the interaction between platelet glycoprotein V and glycoprotein Ib-IX complex.Platelet glycoprotein Ib beta/IX mediates glycoprotein Ib alpha localization to membrane lipid domain critical for von Willebrand factor interaction at high shearSuppressive effect of CORM-2 on LPS-induced platelet activation by glycoprotein mediated HS1 phosphorylation interferenceSignaling events underlying thrombus formation.Role of 14-3-3ζ in platelet glycoprotein Ibα-von Willebrand factor interaction-induced signalingA molecular switch that controls cell spreading and retraction.The interaction of Gα13 with integrin β1 mediates cell migration by dynamic regulation of RhoAPlatelet GPIb-IX-V-dependent signaling.Critical roles for the COOH-terminal NITY and RGT sequences of the integrin beta3 cytoplasmic domain in inside-out and outside-in signalingThe role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activationSignaling-mediated cooperativity between glycoprotein Ib-IX and protease-activated receptors in thrombin-induced platelet activationA functional 14-3-3zeta-independent association of PI3-kinase with glycoprotein Ib alpha, the major ligand-binding subunit of the platelet glycoprotein Ib-IX-V complexSrc family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway.Expression, activation, and function of integrin alphaMbeta2 (Mac-1) on neutrophil-derived microparticlesLIM kinase-1 selectively promotes glycoprotein Ib-IX-mediated TXA2 synthesis, platelet activation, and thrombosis.Defective Association of the Platelet Glycoprotein Ib-IX Complex with the Glycosphingolipid-Enriched Membrane Domain Inhibits Murine Thrombus and Atheroma FormationPlatelet interaction with von Willebrand factor is enhanced by shear-induced clustering of glycoprotein Ibα.14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function.Interaction between platelet glycoprotein Ibalpha and filamin-1 is essential for glycoprotein Ib/IX receptor anchorage at high shear.Platelets and Their Interactions with Other Immune CellsGlycans and the platelet life cycle.Comparison of common platelet receptors between the chacma baboon (Papio ursinus) and human for use in pre-clinical human-targeted anti-platelet studies.New Concepts and Mechanisms of Platelet Activation Signaling.Activation of integrin alpha IIb beta 3 in the glycoprotein Ib-high population of a megakaryocytic cell line, CMK, by inside-out signaling.A critical role for 14-3-3zeta protein in regulating the VWF binding function of platelet glycoprotein Ib-IX and its therapeutic implications.The role of Rac1 in glycoprotein Ib-IX-mediated signal transduction and integrin activation.Regulation of von Willebrand factor binding to the platelet glycoprotein Ib-IX by a membrane skeleton-dependent inside-out signal.A mitogen-activated protein kinase-dependent signaling pathway in the activation of platelet integrin alpha IIbbeta3.Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases.
P2860
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P2860
Analysis of the roles of 14-3-3 in the platelet glycoprotein Ib-IX-mediated activation of integrin alpha(IIb)beta(3) using a reconstituted mammalian cell expression model
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Analysis of the roles of 14-3- ...... ammalian cell expression model
@ast
Analysis of the roles of 14-3- ...... ammalian cell expression model
@en
type
label
Analysis of the roles of 14-3- ...... ammalian cell expression model
@ast
Analysis of the roles of 14-3- ...... ammalian cell expression model
@en
prefLabel
Analysis of the roles of 14-3- ...... ammalian cell expression model
@ast
Analysis of the roles of 14-3- ...... ammalian cell expression model
@en
P2093
P2860
P356
P1476
Analysis of the roles of 14-3- ...... ammalian cell expression model
@en
P2093
P2860
P304
P356
10.1083/JCB.147.5.1085
P407
P577
1999-11-01T00:00:00Z