Induction of topoisomerase I cleavage complexes by the vinyl chloride adduct 1,N6-ethenoadenine.
about
8-Oxoguanine rearranges the active site of human topoisomerase IStructural impact of the leukemia drug 1-beta-D-arabinofuranosylcytosine (Ara-C) on the covalent human topoisomerase I-DNA complexSensitivity of human type II topoisomerases to DNA damage: stimulation of enzyme-mediated DNA cleavage by abasic, oxidized and alkylated lesionsTyrosyl-DNA-phosphodiesterases (TDP1 and TDP2).Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5'-phosphorylated DNA double-strand breaks by replication runoff.Analysis of RuvABC and RecG involvement in the escherichia coli response to the covalent topoisomerase-DNA complexBenzo[a]pyrene diol epoxide adducts in DNA are potent suppressors of a normal topoisomerase I cleavage site and powerful inducers of other topoisomerase I cleavages.The role of topoisomerase I in suppressing genome instability associated with a highly transcribed guanine-rich sequence is not restricted to preventing RNA:DNA hybrid accumulation.Repair of topoisomerase I-mediated DNA damage.Induction of topoisomerase I cleavage complexes by 1-beta -D-arabinofuranosylcytosine (ara-C) in vitro and in ara-C-treated cells.Enhancement of camptothecin-induced topoisomerase I cleavage complexes by the acetaldehyde adduct N2-ethyl-2'-deoxyguanosine.Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages. 7, 8-dihydro-8-oxoguanine and 5-hydroxycytosine.Overexpression of type I topoisomerases sensitizes yeast cells to DNA damage.DNA cleavage assay for the identification of topoisomerase I inhibitors.
P2860
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P2860
Induction of topoisomerase I cleavage complexes by the vinyl chloride adduct 1,N6-ethenoadenine.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Induction of topoisomerase I c ...... ide adduct 1,N6-ethenoadenine.
@en
type
label
Induction of topoisomerase I c ...... ide adduct 1,N6-ethenoadenine.
@en
prefLabel
Induction of topoisomerase I c ...... ide adduct 1,N6-ethenoadenine.
@en
P2093
P2860
P356
P1476
Induction of topoisomerase I c ...... ide adduct 1,N6-ethenoadenine.
@en
P2093
Bjornsti MA
Pourquier P
P2860
P304
27245-27249
P356
10.1074/JBC.273.42.27245
P407
P577
1998-10-01T00:00:00Z