Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes.
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The estrogenic effect of bisphenol A disrupts pancreatic beta-cell function in vivo and induces insulin resistanceIslet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemiaShort-term treatment with bisphenol-A leads to metabolic abnormalities in adult male miceEffects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistanceRole of insulin-like growth factor-binding protein 5 (IGFBP5) in organismal and pancreatic beta-cell growthThe Missing lnc(RNA) between the pancreatic β-cell and diabetesDifferential insulin-like growth factor II (IGF-II) expression: A potential role for breast cancer survival disparity.Increased beta-cell mass by islet transplantation and PLAG1 overexpression causes hyperinsulinemic normoglycemia and hepatic insulin resistance in mice.A compendium of gene expression in normal human tissues.Re-expression of IGF-II is important for beta cell regeneration in adult miceDiabetes and insulin secretion: whither KATP?Glucose transporter-1-deficient mice exhibit impaired development and deformities that are similar to diabetic embryopathy.Effects of genetics and in utero diet on murine pancreatic development.Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted (GHR-KO) mice attenuates phenotypic features of slow agingLeft ventricular dysfunction with reduced functional cardiac reserve in diabetic and non-diabetic LDL-receptor deficient apolipoprotein B100-only miceDifferential expression and signaling activation of insulin receptor isoforms A and B: A link between breast cancer and diabetes.Hyperinsulinism in infancy: from basic science to clinical disease.Transgenerational glucose intolerance with Igf2/H19 epigenetic alterations in mouse islet induced by intrauterine hyperglycemia.Differentially Expressed MicroRNA-483 Confers Distinct Functions in Pancreatic β- and α-Cells.A simple matter of life and death-the trials of postnatal Beta-cell mass regulationExpression of Intratumoral IGF-II Is Regulated by the Gene Imprinting Status in Triple Negative Breast Cancer from Vietnamese Patients.The Association of Early Dietary Supplementation with Vitamin E with the Incidence of Ulcerative Dermatitis in Mice on a C57BL/6 Background: Diet and Ulcerative Dermatitis in Mice.Fine-mapping diabetes-related traits, including insulin resistance, in heterogeneous stock ratsA gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility.Prep1 deficiency induces protection from diabetes and increased insulin sensitivity through a p160-mediated mechanism.Metabolic consequences of pregnancy-associated plasma protein-A deficiency in mice: exploring possible relationship to the longevity phenotype.LDLR-/-ApoB100/100 mice with insulin-like growth factor II overexpression reveal a novel form of retinopathy with photoreceptor atrophy and altered morphology of the retinaPaternal transgenerational glucose intolerance with epigenetic alterations in second generation offspring of GDM.Glucagon-like peptide-1 protects beta-cells against apoptosis by increasing the activity of an IGF-2/IGF-1 receptor autocrine loopGrowth factor control of pancreatic islet regeneration and functionContribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic miceInsulin-like growth factor-II: its role in metabolic and endocrine disease.New insights into the architecture of the islet of Langerhans: a focused cross-species assessment.Insulin-like Growth Factor 2 Overexpression Induces β-Cell Dysfunction and Increases Beta-cell Susceptibility to Damage.Arterial Calcification in Diabetes Mellitus: Preclinical Models and Translational Implications.Beta cell expression of IGF-I leads to recovery from type 1 diabetes.Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor.A Loss-Of-Function Splice Acceptor Variant in IGF2 is Protective for Type 2 Diabetes.A CCR2+ myeloid cell niche required for pancreatic β cell growth.Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes.
P2860
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P2860
Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Transgenic mice overexpressing ...... cells develop type 2 diabetes.
@en
type
label
Transgenic mice overexpressing ...... cells develop type 2 diabetes.
@en
prefLabel
Transgenic mice overexpressing ...... cells develop type 2 diabetes.
@en
P2093
P2860
P50
P921
P356
P1476
Transgenic mice overexpressing ...... cells develop type 2 diabetes
@en
P2093
P2860
P304
P356
10.1172/JCI5656
P407
P577
2000-03-01T00:00:00Z