BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes
about
The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky-Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIαThe schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapseZinc transporter 2 (SLC30A2) can suppress the vesicular zinc defect of adaptor protein 3-depleted fibroblasts by promoting zinc accumulation in lysosomesAssembly and architecture of biogenesis of lysosome-related organelles complex-1 (BLOC-1).AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesisLocalization to mature melanosomes by virtue of cytoplasmic dileucine motifs is required for human OCA2 functionBLOC-2, AP-3, and AP-1 proteins function in concert with Rab38 and Rab32 proteins to mediate protein trafficking to lysosome-related organellesBLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organellesThe dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowthClinical and cellular characterisation of Hermansky-Pudlak syndrome type 6Melanosomes--dark organelles enlighten endosomal membrane transportVesicular trafficking and signaling for cytokine and chemokine secretion in mast cellsFunction and regulation of the endosomal fusion and fission machineriesBLOC-2 targets recycling endosomal tubules to melanosomes for cargo delivery.BORC, a multisubunit complex that regulates lysosome positioning.Yeast homologues of three BLOC-1 subunits highlight KxDL proteins as conserved interactors of BLOC-1.The BLOC-1 complex promotes endosomal maturation by recruiting the Rab5 GTPase-activating protein Msb3.BLOC-3 mutated in Hermansky-Pudlak syndrome is a Rab32/38 guanine nucleotide exchange factorRUTBC1 Functions as a GTPase-activating Protein for Rab32/38 and Regulates Melanogenic Enzyme Trafficking in MelanocytesDysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomesHermansky-Pudlak protein complexes, AP-3 and BLOC-1, differentially regulate presynaptic composition in the striatum and hippocampusCharacterization of rat BLOS2/Ceap, a putative yeast She3 homolog, as interaction partner of apoptosis antagonizing transcription factor/Che-1Phosphatidylinositol-4-kinase type II alpha contains an AP-3-sorting motif and a kinase domain that are both required for endosome trafficRole of dysbindin in dopamine receptor trafficking and cortical GABA functionRoles of BLOC-1 and adaptor protein-3 complexes in cargo sorting to synaptic vesiclesDe novo characterization of the gene-rich transcriptomes of two color-polymorphic spiders, Theridion grallator and T. californicum (Araneae: Theridiidae), with special reference to pigment genesMHC class II presentation of gp100 epitopes in melanoma cells requires the function of conventional endosomes and is influenced by melanosomes.Dysbindin-containing complexes and their proposed functions in brain: from zero to (too) many in a decade.SLC35D3 delivery from megakaryocyte early endosomes is required for platelet dense granule biogenesis and is differentially defective in Hermansky-Pudlak syndrome models.Chemical-genetic disruption of clathrin function spares adaptor complex 3-dependent endosome vesicle biogenesis.BLOC-1 Brings Together the Actin and Microtubule Cytoskeletons to Generate Recycling EndosomesEBAG9 tempers lymphocyte killing activity.Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells.A data-mining approach to rank candidate protein-binding partners-The case of biogenesis of lysosome-related organelles complex-1 (BLOC-1).Dysbindin-1, a schizophrenia-related protein, functionally interacts with the DNA- dependent protein kinase complex in an isoform-dependent manner.Dysregulation of PLDN (pallidin) is a mechanism for platelet dense granule deficiency in RUNX1 haplodeficiency.Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency.Neurodevelopmental disorders: mechanisms and boundary definitions from genomes, interactomes and proteomes.The dystrobrevin-binding protein 1 gene: features and networksAGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.
P2860
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P2860
BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes
description
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im September 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/09/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/09/01)
@nl
наукова стаття, опублікована у вересні 2006
@uk
مقالة علمية (نشرت في سبتمبر 2006)
@ar
name
BLOC-1 interacts with BLOC-2 a ...... otein trafficking on endosomes
@ast
BLOC-1 interacts with BLOC-2 a ...... otein trafficking on endosomes
@en
BLOC-1 interacts with BLOC-2 a ...... otein trafficking on endosomes
@nl
type
label
BLOC-1 interacts with BLOC-2 a ...... otein trafficking on endosomes
@ast
BLOC-1 interacts with BLOC-2 a ...... otein trafficking on endosomes
@en
BLOC-1 interacts with BLOC-2 a ...... otein trafficking on endosomes
@nl
prefLabel
BLOC-1 interacts with BLOC-2 a ...... otein trafficking on endosomes
@ast
BLOC-1 interacts with BLOC-2 a ...... otein trafficking on endosomes
@en
BLOC-1 interacts with BLOC-2 a ...... otein trafficking on endosomes
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
BLOC-1 interacts with BLOC-2 a ...... otein trafficking on endosomes
@en
P2093
Esteban C. Dell'Angelica
Graça Raposo
Michael S. Marks
Santiago M. Di Pietro
Subba R. G. Setty
P2860
P304
P3181
P356
10.1091/MBC.E06-05-0379
P577
2006-09-01T00:00:00Z