Biased distribution of chromosomal breakpoints involving the MLL gene in infants versus children and adults with t(4;11) ALL.
about
Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia.Systematic Classification of Mixed-Lineage Leukemia Fusion Partners Predicts Additional Cancer PathwaysLeukemogenic rearrangements at the mixed lineage leukemia gene (MLL)-multiple rather than a single mechanismFusion of an AF4-related gene, LAF4, to MLL in childhood acute lymphoblastic leukemia with t(2;11)(q11;q23).Diagnostic tool for the identification of MLL rearrangements including unknown partner genesChromosomal rearrangements leading to MLL gene fusions: clinical and biological aspectsDevelopment of five dual-color, double-fusion fluorescence in situ hybridization assays for the detection of common MLL translocation partnersChromosomal translocations involving the MLL gene: molecular mechanisms.Nucleotide-resolution mapping of topoisomerase-mediated and apoptotic DNA strand scissions at or near an MLL translocation hotspotUse of Genome Engineering to Create Patient Specific MLL Translocations in Primary Human Hematopoietic Stem and Progenitor Cells.Premature transcript termination, trans-splicing and DNA repair: a vicious path to cancer.The biological and clinical significance of MLL abnormalities in haematological malignancies.A role for epigenetics in the formation of chromosome translocations in acute leukemia.Etoposide-initiated MLL rearrangements detected at high frequency in human primitive hematopoietic stem cells with in vitro and in vivo long-term repopulating potential.MLL-Rearranged Leukemias-An Update on Science and Clinical Approaches.Mechanism of generation of therapy related leukemia in response to anti-topoisomerase II agents.Identification of MLL partner genes in 27 patients with acute leukemia from a single cytogenetic laboratory.Preferential induction of MLL(Mixed Lineage Leukemia) rearrangements in human lymphocyte cultures treated with etoposide.Genomic anatomy of the specific reciprocal translocation t(15;17) in acute promyelocytic leukemia.New insights to the MLL recombinome of acute leukemias.The distribution of MLL breakpoints correlates with outcome in infant acute leukaemia.A highly specific and sensitive fluorescence in situ hybridization assay for the detection of t(4;11)(q21;q23) and concurrent submicroscopic deletions in acute leukaemias.Low frequency of clonotypic Ig and T-cell receptor gene rearrangements in t(4;11) infant acute lymphoblastic leukaemia and its implication for the detection of minimal residual disease.Clustering of genomic breakpoints at the MLL locus in therapy-related acute leukemia with t(4;11)(q21;q23).Combined effects of the two reciprocal t(4;11) fusion proteins MLL.AF4 and AF4.MLL confer resistance to apoptosis, cell cycling capacity and growth transformation.Complex MLL rearrangements in t(4;11) leukemia patients with absent AF4·MLL fusion alleleThe MLL recombinome of acute leukemiasTranscription linked to recombination: a gene-internal promoter coincides with the recombination hot spot II of the human MLL gene
P2860
Q24538611-A1E702B9-2571-415F-90B6-F4411C52A771Q26771880-23FC1232-36F3-4066-AE29-4CB19C24339BQ26830271-5D018F40-2AEC-44E4-B241-1EB935115687Q30792869-D9E37A1E-6E28-4F23-8BED-7F1E68352735Q33723050-6E376075-CB50-4CA9-AC48-14209ECFA202Q34601806-9AE9627F-2EB5-4C87-83B9-E214EF97B538Q34620470-20F62A51-01B1-42A0-9C1C-08562C234A70Q35128590-11ACD54B-1C6A-4687-BC79-D92522CBD58DQ35221459-6511696A-05D7-41B8-A3A0-CCE2BC64DB88Q35767483-6B3DBE72-868A-4F5D-ABF8-0BB1B44ECB98Q35824956-57804A18-50D9-4ACC-B858-ABBA392077A9Q35854955-6E6CE632-D09A-4D76-8086-0C7927DB0DBDQ37441132-05CF600F-B522-4AE2-9400-2A19E9C7A687Q37463163-35DA62D5-5491-443A-8121-31DAF7E7BAE5Q37633585-F66CBEEF-F2BA-4937-A38A-A69D2BDE7D60Q38029323-730E01D3-E0E2-40CC-9B26-E475790F8D5CQ41133235-AFDC0643-FF89-495B-BD02-B43CF91EC32DQ42063509-1FD970E6-D644-4921-89B2-80516D2F7C26Q44267064-656703DE-DB80-4EDD-8611-2CCDBEA6A37BQ44945193-29E3B9B5-99A7-465B-BB65-65606E4356E5Q46044914-79D061FB-01BA-44B3-BF31-4C257E9C739FQ50760326-63897EE7-088F-4447-906A-EBAA94736F7AQ50760476-59ED7054-986D-4F45-9437-843527A1C98EQ51768538-0F6664B3-B99C-4BD6-A4E8-D4D221AA1D65Q53586148-DB961029-ABE0-4C21-B1D5-A0B059DD47F2Q56965961-4B867E81-B83A-4A61-8AD2-721C978F7273Q56965972-9B21D0CF-3E82-456C-B52A-6DA7B7BA6642Q58492976-6BFFADE2-558F-4293-BA2C-52B77E99F0BE
P2860
Biased distribution of chromosomal breakpoints involving the MLL gene in infants versus children and adults with t(4;11) ALL.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Biased distribution of chromos ...... sus children and adults with t
@nl
Biased distribution of chromos ...... n and adults with t(4;11) ALL.
@en
type
label
Biased distribution of chromos ...... sus children and adults with t
@nl
Biased distribution of chromos ...... n and adults with t(4;11) ALL.
@en
prefLabel
Biased distribution of chromos ...... sus children and adults with t
@nl
Biased distribution of chromos ...... n and adults with t(4;11) ALL.
@en
P2093
P2860
P356
P1433
P1476
Biased distribution of chromos ...... n and adults with t(4;11) ALL.
@en
P2093
Angermüller S
Griesinger F
P2860
P2888
P304
P356
10.1038/SJ.ONC.1204401
P407
P577
2001-05-01T00:00:00Z