Allosteric regulation of protease activity by small molecules.
about
Rational Design of Inhibitors and Activity-Based Probes Targeting Clostridium difficile Virulence Factor TcdBDefining an allosteric circuit in the cysteine protease domain of Clostridium difficile toxinsProperties of protein drug target classesSelf-assembling small molecules form nanofibrils that bind procaspase-3 to promote activationAllosteric Partial Inhibition of Monomeric Proteases. Sulfated Coumarins Induce Regulation, not just Inhibition, of Thrombin.Clostridium difficile toxins: mediators of inflammation.Toward a structural understanding of Clostridium difficile toxins A and B.Fibrils colocalize caspase-3 with procaspase-3 to foster maturation.New approaches for dissecting protease functions to improve probe development and drug discoverySekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300.Recent progress using systems biology approaches to better understand molecular mechanisms of immunity.Synthetic biology approaches to biological containment: pre-emptively tackling potential risks.Discovery of Novel Allosteric Eg5 Inhibitors Through Structure-Based Virtual Screening.The role of toxins in Clostridium difficile infection.Allosteric Site Inhibitor Disrupting Auto-Processing of Malarial Cysteine Proteases
P2860
Q27666020-89AA95D1-85F0-4F09-8020-C712B973B710Q27666963-7D9BC3A8-554A-4F2A-8A93-DF2DD72EBA39Q28545197-DB92B3C1-A22A-46AD-8A26-AFC2C6F33606Q34069805-D8889D6C-D5EF-46F4-9B74-61EDBBED7440Q35981965-640EEAE5-44BD-4B7D-9A5F-720D08F766EDQ36072072-F1D0550C-9F44-4133-94F6-3AB6402B809BQ36159563-087BB561-945D-46F4-9703-04828AA35CB0Q36286189-A0791FD2-08A2-44D7-BB14-902A1D4A2FFFQ36442058-88038E2B-0B1B-43A4-AC92-F919F86DD625Q37011508-618E1621-00FA-491E-9E0E-9D7A94AED8ABQ37325253-D201BE57-527B-4C84-909D-5D169D589B5EQ38383986-BA0A4CE4-A897-4076-B77E-B29C6A5D8950Q38795153-15E56659-F2D9-47C1-9F59-4C84F7E79299Q47734724-174529D3-8996-42A9-BB97-6A14939547A9Q58577506-02E971B7-1F1B-4C46-9F63-10486F77A1C3
P2860
Allosteric regulation of protease activity by small molecules.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Allosteric regulation of protease activity by small molecules.
@ast
Allosteric regulation of protease activity by small molecules.
@en
type
label
Allosteric regulation of protease activity by small molecules.
@ast
Allosteric regulation of protease activity by small molecules.
@en
prefLabel
Allosteric regulation of protease activity by small molecules.
@ast
Allosteric regulation of protease activity by small molecules.
@en
P2860
P356
P1433
P1476
Allosteric regulation of protease activity by small molecules
@en
P2093
Aimee Shen
P2860
P304
P356
10.1039/C003913F
P50
P577
2010-06-10T00:00:00Z