Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase
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G Protein-Coupled Receptors (GPCRs) in Alzheimer's Disease: A Focus on BACE1 Related GPCRsImplications of GABAergic Neurotransmission in Alzheimer's DiseasePhysiological Functions of the β-Site Amyloid Precursor Protein Cleaving Enzyme 1 and 2Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mouse model of Alzheimer's disease.Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects.Alzheimer's disease: relevant molecular and physiopathological events affecting amyloid-β brain balance and the putative role of PPARs.Dysregulation of protein trafficking in neurodegeneration.Significance of transcytosis in Alzheimer's disease: BACE1 takes the scenic route to axons.Altered gut microbiota in female mice with persistent low body weights following removal of post-weaning chronic dietary restriction.Beclin 1 regulates neuronal transforming growth factor-β signaling by mediating recycling of the type I receptor ALK5.Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease.NGF controls APP cleavage by downregulating APP phosphorylation at Thr668: relevance for Alzheimer's disease.Predominant expression of Alzheimer's disease-associated BIN1 in mature oligodendrocytes and localization to white matter tractsFunctions of the Alzheimer's Disease Protease BACE1 at the Synapse in the Central Nervous System.The role of rab proteins in neuronal cells and in the trafficking of neurotrophin receptors.Rab21, a Novel PS1 Interactor, Regulates γ-Secretase Activity via PS1 Subcellular Distribution.Defective Transcytosis of APP and Lipoproteins in Human iPSC-Derived Neurons with Familial Alzheimer's Disease Mutations.Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.Can brain impermeable BACE1 inhibitors serve as anti-CAA medicine?KIF1A mediates axonal transport of BACE1 and identification of independently moving cargoes in living SCG neurons.Molecular neurodegeneration: basic biology and disease pathways.Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer's disease.GGA1 regulates signal-dependent sorting of BACE1 to recycling endosomes, which moderates Aβ production.Disruption of amyloid precursor protein ubiquitination selectively increases amyloid β (Aβ) 40 levels via presenilin 2-mediated cleavage.Bin1 and CD2AP polarise the endocytic generation of beta-amyloid.Tripchlorolide Attenuates β-amyloid Generation via Suppressing PPARγ-Regulated BACE1 Activity in N2a/APP695 Cells.Dysfunction of autophagy and endosomal-lysosomal pathways: Roles in pathogenesis of Down syndrome and Alzheimer's Disease.Neurotransmitter Diversity In Pre-Synaptic Terminals Located in the Parvicellular Neuroendocrine Paraventricular Nucleus of the Rat and Mouse Hypothalamus.β-Secretase BACE1 Promotes Surface Expression and Function of Kv3.4 at Hippocampal Mossy Fiber Synapses.The Association of Amyloid-β Protein Precursor With α- and β-Secretases in Mouse Cerebral Cortex Synapses Is Altered in Early Alzheimer's Disease.Surface Trafficking of APP and BACE in Live Cells.
P2860
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P2860
Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase
@ast
Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase
@en
type
label
Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase
@ast
Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase
@en
prefLabel
Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase
@ast
Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase
@en
P2093
P2860
P356
P1476
Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase
@en
P2093
Celia G Fernandez
Gopal Thinakaran
Jack Waters
Jelita Roseman
Kulandaivelu S Vetrivel
Robert Vassar
Sean Riordan
Virginie Buggia-Prévot
Vytautas P Bindokas
P2860
P2888
P356
10.1186/1750-1326-9-1
P577
2014-01-04T00:00:00Z
P5875
P6179
1004211556