Growth factor receptor-bound protein 2 interaction with the tyrosine-phosphorylated tail of amyloid beta precursor protein is mediated by its Src homology 2 domain.
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Viruses and neurodegenerationThe DISC locus in psychiatric illnessAPP is cleaved by Bace1 in pre-synaptic vesicles and establishes a pre-synaptic interactome, via its intracellular domain, with molecular complexes that regulate pre-synaptic vesicles functionsInteraction of Grb2 SH3 domain with UVRAG in an Alzheimer's disease-like scenario.A new molecular explanation for age-related neurodegeneration: the Tyr682 residue of amyloid precursor proteinCellular levels of Grb2 and cytoskeleton stability are correlated in a neurodegenerative scenario.Tyr(682) in the intracellular domain of APP regulates amyloidogenic APP processing in vivo.First evidence of overlaps between HIV-Associated Dementia (HAD) and non-viral neurodegenerative diseases: proteomic analysis of the frontal cortex from HIV+ patients with and without dementia.Amyloid-beta protein precursor (AbetaPP) intracellular domain-associated protein-1 proteins bind to AbetaPP and modulate its processing in an isoform-specific manner.Novel adaptors of amyloid precursor protein intracellular domain and their functional implications.An intracellular threonine of amyloid-β precursor protein mediates synaptic plasticity deficits and memory loss.A single tyrosine residue in the amyloid precursor protein intracellular domain is essential for developmental function.The intracellular threonine of amyloid precursor protein that is essential for docking of Pin1 is dispensable for developmental function.Y682G Mutation of Amyloid Precursor Protein Promotes Endo-Lysosomal Dysfunction by Disrupting APP-SorLA Interaction.APP is phosphorylated by TrkA and regulates NGF/TrkA signaling.Tyr682 in the Aβ-precursor protein intracellular domain regulates synaptic connectivity, cholinergic function, and cognitive performance.APP Receptor? To Be or Not To Be.The interactome of the amyloid beta precursor protein family members is shaped by phosphorylation of their intracellular domains.Intrinsically unstructured proteins and neurodegenerative diseases: conformational promiscuity at its best.APP physiological and pathophysiological functions: insights from animal models.Neurodegeneration in Alzheimer disease: role of amyloid precursor protein and presenilin 1 intracellular signaling.GRB2 interaction with the ecotropic murine leukemia virus receptor, mCAT-1, controls virus entry and is stimulated by virus binding.Multisite tyrosine phosphorylation of the N-terminus of Mint1/X11α by Src kinase regulates the trafficking of amyloid precursor proteinPolarized transport of Alzheimer amyloid precursor protein is mediated by adaptor protein complex AP1-1B.Amyloid precursor protein and Presenilin1 interact with the adaptor GRB2 and modulate ERK 1,2 signaling.Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration
P2860
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P2860
Growth factor receptor-bound protein 2 interaction with the tyrosine-phosphorylated tail of amyloid beta precursor protein is mediated by its Src homology 2 domain.
description
2004 nî lūn-bûn
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2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
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2004年學術文章
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2004年學術文章
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name
Growth factor receptor-bound p ...... by its Src homology 2 domain.
@en
Growth factor receptor-bound p ...... by its Src homology 2 domain.
@nl
type
label
Growth factor receptor-bound p ...... by its Src homology 2 domain.
@en
Growth factor receptor-bound p ...... by its Src homology 2 domain.
@nl
prefLabel
Growth factor receptor-bound p ...... by its Src homology 2 domain.
@en
Growth factor receptor-bound p ...... by its Src homology 2 domain.
@nl
P2860
P50
P356
P1476
Growth factor receptor-bound p ...... d by its Src homology 2 domain
@en
P2093
Cristiana Noviello
P2860
P304
25374-25380
P356
10.1074/JBC.M400488200
P407
P577
2004-03-30T00:00:00Z