A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence. - Wikidata - awgldk - TriplyDB

A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence.

A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence.

http://www.wikidata.org/entity/Q30699339

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Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance.Solution NMR structure of the ARID domain of human AT-rich interactive domain-containing protein 3A: A human cancer protein interaction network target Functional genetic screen for genes involved in senescence: role of Tid1, a homologue of the Drosophila tumor suppressor l(2)tid, in senescence and cell survival deltaNp73 facilitates cell immortalization and cooperates with oncogenic Ras in cellular transformation in vivo Exploiting orthologue diversity for systematic detection of gain-of-function phenotypes.SUMOylation of DRIL1 directs its transcriptional activity towards leukocyte lineage-specific genes.Functional identification of LRF as an oncogene that bypasses RASV12-induced senescence via upregulation of CYCLIN E.Making sense of cancer genomic data.3'LIFE: a functional assay to detect miRNA targets in high-throughput Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts.MUC4 regulates cellular senescence in head and neck squamous cell carcinoma through p16/Rb pathway.Identification of genetic networks The ARID family transcription factor bright is required for both hematopoietic stem cell and B lineage development.The herpes simplex virus immediate-early ubiquitin ligase ICP0 induces degradation of the ICP0 repressor protein E2FBP1.Cell senescence and hypermitogenic arrest.What has senescence got to do with cancer?Consequence of the tumor-associated conversion to cyclin D1b Systems-level effects of ectopic galectin-7 reconstitution in cervical cancer and its microenvironment.The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor Dissecting cancer pathways and vulnerabilities with RNAi.Functional proteomics approach to investigate the biological activities of cDNAs implicated in breast cancer.Blocking of p53-Snail binding, promoted by oncogenic K-Ras, recovers p53 expression and function.Integrative genomic approaches to understanding cancer.Oncogene-induced senescence: an essential role for Runx.Recent advances in the ARID family: focusing on roles in human cancer.The Bright Side of Hematopoiesis: Regulatory Roles of ARID3a/Bright in Human and Mouse Hematopoiesis.How to become immortal: let MEFs count the ways Towards systematic functional characterization of cancer genomes.Drug target discovery using retroviruses.Role of tissue-specific AT-rich DNA sequence-binding proteins in lymphocyte differentiation.Near-genomewide RNAi screening for regulators of BRAF(V600E) -induced senescence identifies RASEF, a gene epigenetically silenced in melanoma.Novel retroviral vectors to facilitate expression screens in mammalian cells.B-Raf(V600E) signaling deregulates the mitotic spindle checkpoint through stabilizing Mps1 levels in melanoma cells.Loss of Bright/ARID3a function promotes developmental plasticity.A regulated nucleocytoplasmic shuttle contributes to Bright's function as a transcriptional activator of immunoglobulin genes.Runx2 disruption promotes immortalization and confers resistance to oncogene-induced senescence in primary murine fibroblasts.TP53 Regulates Transcription of Cell Cycle Genes TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest TP53 stimulates ARID3A gene expression REKLES is an ARID3-restricted multifunctional domain.

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A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence.

http://www.wikidata.org/entity/Q30699339

description

2002 nî lūn-bûn

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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի փետրվարին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence.

@ast

A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence.

@en

type

label

A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence.

@ast

A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence.

@en

altLabel

A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence

@en

prefLabel

A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence.

@ast

A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence.

@en

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Nature Cell Biology

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A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence.

@en

P2093

Avi Shvarts

http://www.w3.org/2001/XMLSchema#string

Daniel S Peeper

http://www.w3.org/2001/XMLSchema#string

Eugene Y Koh

http://www.w3.org/2001/XMLSchema#string

Sirith Douma

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Thijn Brummelkamp

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P2860

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

A novel E2F binding protein with Myc-type HLH motif stimulates E2F-dependent transcription by forming a heterodimer

The immunoglobulin heavy-chain matrix-associating regions are bound by Bright: a B cell-specific trans-activator that describes a new DNA-binding protein family

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

Regulation of the cyclin E gene by transcription factor E2F1

Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins.

ARID proteins come in from the desert.

Differential effects of p19(Arf) and p16(Ink4a) loss on senescence of murine bone marrow-derived preB cells and macrophages.

Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor.

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148-153

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10.1038/NCB742

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2

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4

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George Q. Daley

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2002-02-01T00:00:00Z

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11546499

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1047660885

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11812999

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