Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand breaks in mitotic cells.
about
Reduction of nucleosome assembly during new DNA synthesis impairs both major pathways of double-strand break repairGenome wide distribution of illegitimate recombination events in Kluyveromyces lactisMre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break RepairDifferences in the DNA replication of unicellular eukaryotes and metazoans: known unknownsMre11 and Ku regulation of double-strand break repair by gene conversion and break-induced replication.Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex.Relative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double-strand break repair by homologous recombination in both the chicken DT40 and human TK6 cell linesIdentification of Plasmodium falciparum DNA Repair Protein Mre11 with an Evolutionarily Conserved Nuclease FunctionInterplay of Mre11 nuclease with Dna2 plus Sgs1 in Rad51-dependent recombinational repair.Mre11-Rad50 promotes rapid repair of DNA damage in the polyploid archaeon Haloferax volcanii by restraining homologous recombinationRAD50 is required for efficient initiation of resection and recombinational repair at random, gamma-induced double-strand break endsBi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks.MRE11 function in response to topoisomerase poisons is independent of its function in double-strand break repair in Saccharomyces cerevisiaeMre11 nuclease activity and Ctp1 regulate Chk1 activation by Rad3ATR and Tel1ATM checkpoint kinases at double-strand breaks.The fission yeast Rad32(Mre11)-Rad50-Nbs1 complex acts both upstream and downstream of checkpoint signaling in the S-phase DNA damage checkpointA mechanism of palindromic gene amplification in Saccharomyces cerevisiae.Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.Mutagenesis dependent upon the combination of activation-induced deaminase expression and a double-strand breakChromosome integrity at a double-strand break requires exonuclease 1 and MRXEnd-processing during non-homologous end-joining: a role for exonuclease 1Mutations in Mre11 phosphoesterase motif I that impair Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex stability in addition to nuclease activityDNA repair factor MRE11/RAD50 cleaves 3'-phosphotyrosyl bonds and resects DNA to repair damage caused by topoisomerase 1 poisons.ATP hydrolysis by RAD50 protein switches MRE11 enzyme from endonuclease to exonuclease.The role of nonhomologous end-joining components in telomere metabolism in Kluyveromyces lactisRequirement of POL3 and POL4 on non-homologous and microhomology-mediated end joining in rad50/xrs2 mutants of Saccharomyces cerevisiae.One identity or more for telomeres?RAD59 is required for efficient repair of simultaneous double-strand breaks resulting in translocations in Saccharomyces cerevisiaeProcessing of DNA double-stranded breaks and intermediates of recombination and repair by Saccharomyces cerevisiae Mre11 and its stimulation by Rad50, Xrs2, and Sae2 proteins.Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation.Inhibition of DNA double-strand break repair by the Ku heterodimer in mrx mutants of Saccharomyces cerevisiae.The role of MRN in the S-phase DNA damage checkpoint is independent of its Ctp1-dependent roles in double-strand break repair and checkpoint signaling.DNA damage responses in Drosophila nbs mutants with reduced or altered NBS function.Coordination and processing of DNA ends during double-strand break repair: the role of the bacteriophage T4 Mre11/Rad50 (MR) complex.Consider the workhorse: Nonhomologous end-joining in budding yeast.Mutations of the Yku80 C terminus and Xrs2 FHA domain specifically block yeast nonhomologous end joiningRad52 Inverse Strand Exchange Drives RNA-Templated DNA Double-Strand Break Repair.Alpha3, a transposable element that promotes host sexual reproductionTelomerase- and Rad52-independent immortalization of budding yeast by an inherited-long-telomere pathway of telomeric repeat amplification.Nonhomologous End-Joining with Minimal Sequence Loss Is Promoted by the Mre11-Rad50-Nbs1-Ctp1 Complex in Schizosaccharomyces pombe.The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends.
P2860
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P2860
Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand breaks in mitotic cells.
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2004 nî lūn-bûn
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2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2004 թվականի ապրիլին հրատարակված գիտական հոդված
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2004年の論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年论文
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Role of the nuclease activity ...... trand breaks in mitotic cells.
@ast
Role of the nuclease activity ...... trand breaks in mitotic cells.
@en
Role of the nuclease activity ...... trand breaks in mitotic cells.
@nl
type
label
Role of the nuclease activity ...... trand breaks in mitotic cells.
@ast
Role of the nuclease activity ...... trand breaks in mitotic cells.
@en
Role of the nuclease activity ...... trand breaks in mitotic cells.
@nl
prefLabel
Role of the nuclease activity ...... trand breaks in mitotic cells.
@ast
Role of the nuclease activity ...... trand breaks in mitotic cells.
@en
Role of the nuclease activity ...... trand breaks in mitotic cells.
@nl
P2093
P2860
P1433
P1476
Role of the nuclease activity ...... strand breaks in mitotic cells
@en
P2093
Francesca Storici
L Kevin Lewis
Patrick Sung
Shanna Calero
Stephen Van Komen
P2860
P304
P356
10.1534/GENETICS.166.4.1701
P407
P577
2004-04-01T00:00:00Z