Localization of Mad2 to kinetochores depends on microtubule attachment, not tension - Test2 - elhamkhani - TriplyDB

Localization of Mad2 to kinetochores depends on microtubule attachment, not tension

Localization of Mad2 to kinetochores depends on microtubule attachment, not tension

http://www.wikidata.org/entity/Q29620330

about

Tip1/CLIP-170 protein is required for correct chromosome poleward movement in fission yeast Bub3 is a spindle assembly checkpoint protein regulating chromosome segregation during mouse oocyte meiosis Caenorhabditis elegans cyclin B3 is required for multiple mitotic processes including alleviation of a spindle checkpoint-dependent block in anaphase chromosome segregation Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1 Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2beta The DYNLT3 light chain directly links cytoplasmic dynein to a spindle checkpoint protein, Bub3 Zwilch, a new component of the ZW10/ROD complex required for kinetochore functions Identification of two novel components of the human NDC80 kinetochore complex Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension FAT10 plays a role in the regulation of chromosomal stability Shugoshin is a Mad1/Cdc20-like interactor of Mad2 The human spindle assembly checkpoint protein Bub3 is required for the establishment of efficient kinetochore-microtubule attachments.Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint.Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2 The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A Identification of a MAD2-binding protein, CMT2, and its role in mitosis.Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint.Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints Microtubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied.Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation The centromere geometry essential for keeping mitosis error free is controlled by spindle forces Inhibition of centromere dynamics by eribulin (E7389) during mitotic metaphase Taxol suppresses dynamics of individual microtubules in living human tumor cells Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2 hNuf2 inhibition blocks stable kinetochore-microtubule attachment and induces mitotic cell death in HeLa cells The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling Spindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activity Mad2 transiently associates with an APC/p55Cdc complex during mitosis Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochores Human MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochores Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.Centrosomes, chromosome instability (CIN) and aneuploidy

P2860

Q21136373-1FED3F18-6C64-428B-82D6-6842E3DCE37A Q21142712-2F26BD11-AEB4-4948-B103-1F14754FB3A8 Q21558513-B33DC3EE-E581-43D7-A718-4063846449BE Q22003896-5CEA9AC1-8859-4455-A89C-9730C5EC8FB3 Q22010522-517CC784-1C9B-4A4E-91C2-933B162FFC90 Q22010696-6DD82265-91B2-49DF-B57E-2A53627DFBB0 Q24296443-03D186AE-C5EB-447A-8E82-959EE6505CA7 Q24299625-57A8A73A-FBD8-4340-A64B-43F702703016 Q24303613-271666FF-0E49-4466-9F7F-9F1B3C095F60 Q24305061-A6DE63F4-315E-475F-A11D-5DBF8882120B Q24305422-9E5EE119-4BB0-443C-BBC0-D0112850629F Q24306351-5BED4F12-3EC5-4C02-98D2-D41F205145B0 Q24306626-40C04E38-33AC-4D3D-99BF-46B9597E9001 Q24312788-4F7FFCA1-CE70-456B-85B5-0F9552BBFC64 Q24313155-A016BEC1-69DB-42C0-BFE5-7BEFD8161191 Q24316058-F1739F41-FD74-4269-BEFF-80D4BD3773C8 Q24316292-A4CFE018-9F82-471C-B9A9-CD4AD77C7850 Q24318410-2F0281D5-E130-4DAE-AC25-F198E509F29D Q24321983-D3C7A4D5-71D8-4659-8C45-18F84B13677E Q24534571-90AC7415-2415-46E9-AECC-7F64B4205F2E Q24548359-63083732-B717-4733-9C3D-C7E339D3B560 Q24555706-680F230B-8E72-435F-A87A-D5D58991061A Q24600680-66EEA4ED-E595-42F9-9FD0-33494D058719 Q24635263-B692585A-98D1-42F1-84B3-2D9665F6D50C Q24642588-F69A7085-5039-4033-8B6E-8075056A7B35 Q24652311-13EE8B78-0D87-4A8A-AAB2-667897CFE4FB Q24654805-4A9FAABD-CE01-4BA1-971C-4F7A36AF26E4 Q24657514-DEABD0DE-EA31-4AFD-A2C9-2DC63EA213AD Q24657911-2D027201-1825-4D1C-B26D-A50FCBF19F26 Q24670095-1A6A20CF-012A-49F5-9BC0-F75F59CC754F Q24674081-26BC4561-9823-4DED-B1C1-422E097EAF68 Q24675117-2E2200E3-94E8-41C2-9C3B-8488D089A9E2 Q24679267-8A496481-8752-4D25-B5B3-1342B4AEA17E Q24679269-8216FC34-446E-45E8-BA0F-5852CE34FA38 Q24682864-6B73A749-BC05-4E7A-A80B-972026D649FD Q24682946-A5EE57C9-E2FA-453D-838D-08C380C2D4AC Q24682987-6872F585-184B-4409-8463-DAE06A720D3D Q24683942-100DF6FE-A455-403D-89BD-6894C79FBB16 Q24685871-9691E39D-C8A0-44AC-9C21-639BE96D13AB Q26865035-D063BB95-255C-4122-8DEA-7C146EE094EB

P2860

Localization of Mad2 to kinetochores depends on microtubule attachment, not tension

http://www.wikidata.org/entity/Q29620330

description

1998 nî lūn-bûn

@nan

1998 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի հունիսին հրատարակված գիտական հոդված

@hy

1998年の論文

@ja

1998年論文

@yue

1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu

name

Localization of Mad2 to kinetochores depends on microtubule attachment, not tension

@ast

Localization of Mad2 to kinetochores depends on microtubule attachment, not tension

@en

type

label

Localization of Mad2 to kinetochores depends on microtubule attachment, not tension

@ast

Localization of Mad2 to kinetochores depends on microtubule attachment, not tension

@en

prefLabel

Localization of Mad2 to kinetochores depends on microtubule attachment, not tension

@ast

Localization of Mad2 to kinetochores depends on microtubule attachment, not tension

@en

P1433

Q29620330-D40D85B1-CBD2-4D81-8927-2FBCB9A1BFA7

P1476

Q29620330-E5BB4FF1-11C3-4300-8787-4535751212AD

P2093

Q29620330-20100367-3422-4664-9EC6-D49FB67ADD7B

Q29620330-42F77526-81F8-4907-80C4-F4CC45E7E34B

Q29620330-6167255A-1C2C-4463-A5E9-4BD3FCFFF344

Q29620330-B613C08D-2C83-4D30-A6CA-E905BAF50F66

P2860

Q29620330-032D64A5-926C-4EBA-A9EC-38BCAD7DD5D8

Q29620330-09FF372A-9AF6-4FB4-8386-DC7D868017E2

Q29620330-119D44DB-57F3-4384-96AA-5661D6DB7335

Q29620330-162B8A3D-A607-46AB-ADF7-749667BEEA1A

Q29620330-3868D69E-DD6A-4AB8-8B03-B6F830702F9F

Q29620330-3D5B303B-9DD0-4284-BD82-5E6F6F5BC77C

Q29620330-4CDBD41D-DB0D-4B1F-9ABE-AF70E51AE797

Q29620330-4FA3C819-86DE-4C73-8591-004528206268

Q29620330-52D8BE9E-4207-41F4-B26E-0273D8E8B228

Q29620330-5A485F51-6533-48B2-B675-4F2C088F9E44

P304

Q29620330-F6B0C64B-27AF-4088-89BD-F038B6D336EA

P31

Q29620330-E35C8FC3-8946-4192-A4D6-EC6C3F795129

P3181

Q29620330-CFA59FF8-4819-4EF9-97D3-8420097C3417

P356

Q29620330-66A278C7-2CB0-4553-B0EC-855DAC70562E

P407

Q29620330-ABDC78D3-3993-40D7-BFDF-6247945C7CC7

P433

Q29620330-F6257923-6379-4A3A-B9BF-5DC466CF8B44

P478

Q29620330-958A6CB6-6CF2-41E2-88E7-F66F9AED8F43

P577

Q29620330-2046382C-179D-40B0-B74A-2378A4011433

P5875

Q29620330-DE5FF291-4EEE-4316-A808-5396CAFC8233

P698

Q29620330-1D29E1D2-F18B-44F8-9B1B-75F97968FA4C

P921

Q29620330-0AE9E6A9-0131-4974-8224-F0569BE91287

Q29620330-F27547F7-1A6C-4813-9113-7567A25537A0

P932

Q29620330-9852E29A-2BA4-40E3-80C0-A67D8D7B19C5

P3181

P356

P1433

Journal of Cell Biology

P1476

Localization of Mad2 to kinetochores depends on microtubule attachment, not tension

@en

P2093

A W Murray

http://www.w3.org/2001/XMLSchema#string

E D Salmon

http://www.w3.org/2001/XMLSchema#string

J C Waters

http://www.w3.org/2001/XMLSchema#string

R H Chen

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of a human mitotic checkpoint gene: hsMAD2

Centromere DNA mutations induce a mitotic delay in Saccharomyces cerevisiae

MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity

Checkpoint genes required to delay cell division in response to nocodazole respond to impaired kinetochore function in the yeast Saccharomyces cerevisiae.

The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores

Aberrantly segregating centromeres activate the spindle assembly checkpoint in budding yeast

Motile kinetochores and polar ejection forces dictate chromosome position on the vertebrate mitotic spindle

Kinetochore fiber maturation in PtK1 cells and its implications for the mechanisms of chromosome congression and anaphase onset

The Schizosaccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex

S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function.

P304

1181-1191

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

2295771

http://www.w3.org/2001/XMLSchema#string

P356

10.1083/JCB.141.5.1181

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

141

http://www.w3.org/2001/XMLSchema#string

P577

1998-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

277432261

http://www.w3.org/2001/XMLSchema#string

P698

9606210

http://www.w3.org/2001/XMLSchema#string

P921

P932

2137189

http://www.w3.org/2001/XMLSchema#string