Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation
about
Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpointAbraxas and RAP80 form a BRCA1 protein complex required for the DNA damage responseDNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domainsDTL/CDT2 is essential for both CDT1 regulation and the early G2/M checkpointNormal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases.PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpointsInvolvement of human MOF in ATM functionA human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints.Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpointRereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpointHuman Claspin works with BRCA1 to both positively and negatively regulate cell proliferationChk2 phosphorylation of BRCA1 regulates DNA double-strand break repairBMI1-mediated histone ubiquitylation promotes DNA double-strand break repairInvolvement of nucleotide excision and mismatch repair mechanisms in double strand break repairInvolvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damageEssential and dispensable roles of ATR in cell cycle arrest and genome maintenanceDynamic Duo-The Salmonella Cytolethal Distending Toxin Combines ADP-Ribosyltransferase and Nuclease Activities in a Novel Form of the Cytolethal Distending ToxinChemically enhanced radiotherapy: visions for the futureDAB2IP in cancerTaselisib (GDC-0032), a Potent β-Sparing Small Molecule Inhibitor of PI3K, Radiosensitizes Head and Neck Squamous Carcinomas Containing Activating PIK3CA Alterations.DNA-PKcs-PIDDosome: a nuclear caspase-2-activating complex with role in G2/M checkpoint maintenanceTranscriptional repression of Cdc25B by IER5 inhibits the proliferation of leukemic progenitor cells through NF-YB and p300 in acute myeloid leukemiaThe RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteinsThe effects of G2-phase enrichment and checkpoint abrogation on low-dose hyper-radiosensitivityMutation of the mouse Rad17 gene leads to embryonic lethality and reveals a role in DNA damage-dependent recombinationEpstein-Barr virus-encoded latent membrane protein 1 impairs G2 checkpoint in human nasopharyngeal epithelial cells through defective Chk1 activationDNA replication defects, spontaneous DNA damage, and ATM-dependent checkpoint activation in replication protein A-deficient cells.Topoisomerase II and histone deacetylase inhibitors delay the G2/M transition by triggering the p38 MAPK checkpoint pathwayATR-dependent checkpoint modulates XPA nuclear import in response to UV irradiationChk1 kinase negatively regulates mitotic function of Cdc25A phosphatase through 14-3-3 bindingTransient inhibition of ATM kinase is sufficient to enhance cellular sensitivity to ionizing radiationIn vitro and in vivo radiosensitization with AZD6244 (ARRY-142886), an inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 kinaseMicrohomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex.Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX.MEPE/OF45 as a new target for sensitizing human tumour cells to DNA damage inducersCaffeine and human DNA metabolism: the magic and the mystery.Effects of ionizing radiation on biological molecules--mechanisms of damage and emerging methods of detectionVertebrate cells genetically deficient for Cdc14A or Cdc14B retain DNA damage checkpoint proficiency but are impaired in DNA repair.
P2860
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P2860
Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Two molecularly distinct G
@nl
Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation
@ast
Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation
@en
type
label
Two molecularly distinct G
@nl
Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation
@ast
Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation
@en
prefLabel
Two molecularly distinct G
@nl
Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation
@ast
Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation
@en
P2093
P2860
P1476
Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation
@en
P2093
Dae-Sik Lim
Michael B Kastan
Seong-Tae Kim
P2860
P304
P356
10.1128/MCB.22.4.1049-1059.2002
P407
P577
2002-02-01T00:00:00Z