Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney
about
PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12mTOR signaling in growth control and diseaseNovel nervous and multi-system regenerative therapeutic strategies for diabetes mellitus with mTORStem cell guidance through the mechanistic target of rapamycinCutting through the complexities of mTOR for the treatment of strokeShedding new light on neurodegenerative diseases through the mammalian target of rapamycinUbl4A is required for insulin-induced Akt plasma membrane translocation through promotion of Arp2/3-dependent actin branchingErythropoietin and mTOR: A "One-Two Punch" for Aging-Related Disorders Accompanied by Enhanced Life ExpectancyJudicious Toggling of mTOR Activity to Combat Insulin Resistance and Cancer: Current Evidence and PerspectivesTBCK influences cell proliferation, cell size and mTOR signaling pathwaymTOR signaling in tumorigenesisThe Complex Roles of Mechanistic Target of Rapamycin in Adipocytes and Beyond.Estradiol Suppresses TLR4-triggered Apoptosis of Decidual Stromal Cells and Drives an Anti-inflammatory TH2 Shift by Activating SGK1.mTORC2 in the center of cancer metabolic reprogrammingRegulation of blood-testis barrier (BTB) dynamics during spermatogenesis via the "Yin" and "Yang" effects of mammalian target of rapamycin complex 1 (mTORC1) and mTORC2.mTORC2 activity in brain cancer: Extracellular nutrients are required to maintain oncogenic signaling.The evolution of the TOR pathway and its role in cancer.Taking aim at Alzheimer's disease through the mammalian target of rapamycinThe mTOR signaling pathway as a treatment target for intracranial neoplasmsmSIN1 protein mediates SGK1 protein interaction with mTORC2 protein complex and is required for selective activation of the epithelial sodium channel.The mTOR (mammalian target of rapamycin) kinase maintains integrity of mTOR complex 2.Deconvoluting mTOR biologyIntegrity of mTORC2 is dependent on the rictor Gly-934 site.mTOR complex 2 signaling and functionsMammalian target of rapamycin signaling in diabetic cardiovascular diseaseA TORC2-Akt Feed-Forward Topology Underlies HER3 Resiliency in HER2-Amplified Cancers.A Critical Kinase Cascade in Neurological Disorders: PI 3-K, Akt, and mTOR.mTOR: on target for novel therapeutic strategies in the nervous system.mTOR: a link from the extracellular milieu to transcriptional regulation of oligodendrocyte development.mTORC2 critically regulates renal potassium handling.Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitors.Mechanistically distinct cancer-associated mTOR activation clusters predict sensitivity to rapamycin.Therapeutic targeting of autophagy in disease: biology and pharmacology.NDRG1 overexpression promotes the progression of esophageal squamous cell carcinoma through modulating Wnt signaling pathway.Regulation of OSR1 and the sodium, potassium, two chloride cotransporter by convergent signals.Functionally distinct PI 3-kinase pathways regulate myelination in the peripheral nervous system.Targeting mTOR network in colorectal cancer therapyTargeting the Mammalian Target of Rapamycin in Lung Cancer.mTOR function and therapeutic targeting in breast cancer.mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused.
P2860
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P248
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P2860
Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney
description
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
@ast
im Mai 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/05/15)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/05/15)
@nl
наукова стаття, опублікована в травні 2011
@uk
مقالة علمية (نشرت في 15-5-2011)
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name
Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney
@ast
Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney
@en
Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney
@nl
type
label
Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney
@ast
Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney
@en
Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney
@nl
prefLabel
Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney
@ast
Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney
@en
Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney
@en
P2093
Eeva M Sommer
Kei Sakamoto
Stephan Wullschleger
P2860
P304
P3181
P356
10.1042/BJ20102103
P407
P577
2011-05-01T00:00:00Z